Results 211 to 220 of about 794,896 (338)
The Link Between R&D Subsidies, R&D Spending and Technological Performance [PDF]
This paper analyzes the effects of public R&D funding on R&D expenditure and patenting behavior of German firms. The main focus is the direct impact of subsidies on R&D and the indirect effect on innovation output measured by patent applications.
Czarnitzki, Dirk, Hussinger, Katrin
core
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Identification of the Key Fields and Their Key Technical Points of Oncology by Patent Analysis. [PDF]
PLoS One, 2015 Zhang T, Chen J, Jia X.
europepmc +1 more source
A Critical Analysis of the Proposed National Patent Board
, 1998 Richard P. Cusick +3 more
openalex +1 more source
Deduction of Vacant Technology through Patent Analysis in Disaster-Safety Positioning Technologies
, 2013 Hangwon Lee, Youngok Kim
openalex +1 more source
IN SEARCH OF THE PRIVATELY OPTIMAL PATENT BREADTH [PDF]
Innovating firms choose to patent their innovations when patenting allows the appropriation of more rents than do other forms of intellectual property protection (e.g., trade secrecy).
Fulton, Murray E., Yiannaka, Amalia
core +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
The development of synthetic biology: a patent analysis. [PDF]
Syst Synth Biol, 2013 van Doren D, Koenigstein S, Reiss T.
europepmc +1 more source
Patent Foramen Ovale Closure for Recurrent Stroke Prevention: A Network Meta-Analysis of Randomized Controlled Trials [PDF]
, 2018 George Mina, Demiana Soliman, Kalgi Modi
openalex +1 more source