Results 41 to 50 of about 1,552,229 (290)

Antibody therapeutics – the evolving patent landscape

open access: yesNew Biotechnology, 2011
The antibody patent landscape has evolved dramatically over the past 30 years, particularly in areas of technology relating to antibody modification to reduce immunogenicity in humans or improve antibody function. In some cases antibody techniques that were developed in the 1980s are still the subject of patent protection in the United States or Canada.
Jenny, Petering   +2 more
openaire   +2 more sources

A Reproducible Patent Landscape Review Framework for Search Validation, Dataset Construction and Structured Research Whitespace Assessment

open access: yesInventions
Patent Landscape Reviews (PLRs) are widely used to map technological activity, applicants, jurisdictions, patent families and innovation trends. However, many PLRs remain descriptive and provide limited methodological detail on search validation, dataset
Pg Emeroylariffion Abas
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The dental patent landscape in Saudi Arabia: A comprehensive review

open access: yesSaudi Journal of Oral Sciences
Patents play a vital role in protecting the intellectual property of inventors and serve as key indicators of a nation’s advancement. The Patent Cooperation Treaty simplifies the international patent application process, aiding inventors in seeking ...
Sultan A. Aldakhil   +2 more
doaj   +1 more source

Patent Enforcement: A Comparative Review Preventing Patent Trolling in Europe

open access: yesThe Annals of “Dunarea de Jos” University of Galati. Fascicle IX, Metallurgy and Materials Science, 2018
The US has made significant progress in the patent legislation landscape as evidenced by the US Patent Act in the Constitution and America Invents Act (AIA) of 2011.
Benjamin FRANCO, Cristian BANACU
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Recent legal developments from a nanotechnology perspective

open access: yesNanotechnology Reviews, 2012
With the recent major changes to the patent law system, it is more important than ever for nanotechnology-based companies to reevaluate their patent strategy.
Thiessen Rose, Lozan Vladimir
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Emerging antibody-drug conjugate (ADC) therapies: perspectives from the global patent landscape

open access: yesFrontiers in Pharmacology
BackgroundAntibody-drug conjugates (ADCs) represent one of the most significant innovations in biopharmaceutical research, integrating antibody target specificity with the cytotoxic potency of small-molecule payloads.
Tong Wu   +4 more
doaj   +1 more source

Patent Searching for STEM Researchers.

open access: yesIssues in Science and Technology Librarianship, 2015
Entrepreneurship and intellectual property (IP) management have become a focus of academic institutions over the past decade. This webliography is intended to help guide researchers and inventors to the patent information they need in order to advance ...
John J. Meier
doaj   +1 more source

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