Results 41 to 50 of about 773,443 (250)

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

FEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui, Agnes Banreti, Armelle L. Ernst, Guillaume Leseigneur, Uwe J. Meierhenrich   +4 more
wiley   +1 more source

Patent Analytics Based on Feature Vector Space Model: A Case of IoT

IEEE Access, 2019
The number of approved patents worldwide increases rapidly each year, which requires new patent analytics to efficiently mine the valuable information attached to these patents.
Lei Lei, Jiaju Qi, Kan Zheng
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Optimizing Patent Prior Art Search: An Approach Using Patent Abstract and Key Terms

Information
The rapid advancement of technology has led to a sustained accumulation of patent documents globally, as newly filed applications add to an ever-expanding repository of prior art.
Amna Ali, Mohammad Ali Humayun, Liyanage Chandratilak De Silva, Pg Emeroylariffion Abas   +3 more
doaj   +1 more source

Using the Citation-Content-Based Approach to Patent Clustering [PDF]

International Journal of Information Science and Management
patents are a significant competitive strategy to categorize commercial value based on the source information of technology; researchers use patent analysis as a practical tool to infer various types of information.
Narges Neshat, Anahita Kermani
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

United we fall, divided we stand: A study of query segmentation and PRF for patent prior art search [PDF]

, 2011
Previous research in patent search has shown that reducing queries by extracting a few key terms is ineffective primarily because of the vocabulary mismatch between patent applications used as queries and existing patent documents. This finding has led to
Ganguly, Debasis, Leveling, Johannes, Jones, Gareth J.F.   +2 more
core   +2 more sources

Big Data Related Patent Retrieval System Based on Filtering Rules

Journal of Computing and Information Technology
In the information age, patents are an important carrier of scientific research achievements. How to protect patents and effectively transmit them has become an important development measure in the current information age.
Xuanrong Zhao
doaj   +1 more source

Patent Keyword Extraction Algorithm Based on Distributed Representation for Patent Classification

Entropy, 2018
Many text mining tasks such as text retrieval, text summarization, and text comparisons depend on the extraction of representative keywords from the main text.
Jie Hu, Shaobo Li, Yong Yao, Liya Yu, Guanci Yang, Jianjun Hu   +5 more
doaj   +1 more source