Results 51 to 60 of about 55,114 (258)
Three-Layer Retrieval and Self-Evaluation Classification Method Based on FastText Algorithm
IEEE AccessPatent big data serves as a valuable scientific research source for technological innovation, enabling breakthroughs beyond existing knowledge and fostering disruptive ideas.
Yidan Li, Huanhuan Hong, Luhong Wen
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Patent Searching for STEM Researchers.
Issues in Science and Technology Librarianship, 2015 Entrepreneurship and intellectual property (IP) management have become a focus of academic institutions over the past decade. This webliography is intended to help guide researchers and inventors to the patent information they need in order to advance science and protect their IP.
openaire +2 more sources
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
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Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
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Patenting of technologies related to renewable energy: the case of biodiesel
Revista Tecnologia, 2010 In this work a study of technological tendencies in biodiesel was carried out, based on information extracted of patent documents. The term “patent document” covers published patent applications or granted patents.
Márcia França Fernandes dos Santos +2 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Optimizing Patent Prior Art Search: An Approach Using Patent Abstract and Key Terms
InformationThe rapid advancement of technology has led to a sustained accumulation of patent documents globally, as newly filed applications add to an ever-expanding repository of prior art.
Amna Ali +3 more
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
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Механика машин, механизмов и материалов, 2016 The main reasons for the increasing competitiveness of domestic products are reduction of the standards role, the enterprises inability to pursue full research and fear of participation in the scientific and technical programs, optionality of realization
Vladimir B. Algin
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