Results 61 to 70 of about 3,142,408 (281)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Three-Layer Retrieval and Self-Evaluation Classification Method Based on FastText Algorithm

open access: yesIEEE Access
Patent big data serves as a valuable scientific research source for technological innovation, enabling breakthroughs beyond existing knowledge and fostering disruptive ideas.
Yidan Li, Huanhuan Hong, Luhong Wen
doaj   +1 more source

Exploitation and Utilization of patent Information on Internet

open access: yes浙江大学学报. 农业与生命科学版, 2005
Being the publication that occupies 1/4 of gross publishing quantities all over the world, patent documentation plays an important role in the development of science and technology in universities.
ZHANG Yun-lan
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Patent Searching for STEM Researchers.

open access: yesIssues in Science and Technology Librarianship, 2015
Entrepreneurship and intellectual property (IP) management have become a focus of academic institutions over the past decade. This webliography is intended to help guide researchers and inventors to the patent information they need in order to advance science and protect their IP.
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Patenting of technologies related to renewable energy: the case of biodiesel

open access: yesRevista Tecnologia, 2010
In this work a study of technological tendencies in biodiesel was carried out, based on information extracted of patent documents. The term “patent document” covers published patent applications or granted patents.
Márcia França Fernandes dos Santos   +2 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

European Patent Office's 1995 Search Report

open access: yes, 1995
European Patent Office's 1995 search report listing relevant documents for assessing whether the claimed invention is new (and involves an inventive step) for European Patent Application 95 30 5602.
European Patent Office
core   +1 more source

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