Results 61 to 70 of about 202,256 (287)
Harvesting the uncollected fruits of other people’s intellectual labour [PDF]
, 2017 Intellectual property regimes necessarily create artificial scarcity leading to wastage, both by blocking follow-up research and hindering access to those who are only able to pay less then the actual retail price.
Timmermann, Cristian
core +2 more sources
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source
La Propiedad Inmaterial, 2011 Los sistemas de patentes en los países desarrollados han hecho diferentes interpretaciones o creado nuevos estándares con el fin de adoptar secuencias de ADN como una entidad patentable, independientemente del hecho de que el ADN en principio no cumplía ...
Carlos Augusto Conde Gutiérrez
doaj +2 more sources
Núcleo de apoio ao patenteamento: manual de procedimentos. [PDF]
, 2011 Patentes; Busca; Redação; Formulários; Cartasbitstream/item/26301/1/DOC14-2005.pdf; bitstream/item/26303/1/DOC14-2005-anexos.pdfAcompanha folheto contendo os ...
GONTOW, R. +2 more
core
Low Incidence of Relapses After Vaccination in Anti‐Aquaporin‐4 Antibody‐Positive NMOSD
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Patients with neuromyelitis optica spectrum disorder (NMOSD) may experience increased signs and symptoms of their underlying disease when vaccinated against meningococcal disease before receiving complement component 5 inhibitor therapies. This retrospective analysis indicated an overall low relapse incidence (mean [range], 3.3% [0.7%–10.6 ...
Sean J. Pittock +4 more
wiley +1 more source
Patentes y crecimiento económico, el caso de México durante el TLCAN
Economía Teoría y Práctica, 2018 Tras caracterizar la naturaleza de las patentes concedidas en México por el Instituto Mexicano de la Propiedad Intelectual (IMPI), el objetivo de este artículo es examinar la relación entre el número de patentes de residentes y el crecimiento económico ...
Alenka Guzmán +2 more
doaj +1 more source
The Regulation of Competition and Innovation in the European Union and Spain: Opportunities for the Philippines and the ASEAN [PDF]
, 2016 The Philippines are currently facing a process of regional economic integration inside the ASEAN, in some way similar to the process undertaken by Spain and the European Union decades ago.
Olmedo-Peralta, Eugenio
core
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
De fronteras y patentes farmaceúticas [PDF]
, 2014 Desde que el ADPIC armoniza los estándares de protección de las patentes de invención en el progresivamente ampliado número de Estados miembros de la OMC, las fronteras estatales y sociales del acceso a los medicamentos fueron llevadas al primer plano
Otero García-Castrillón, Carmen
core +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Annals of Clinical and Translational Neurology, EarlyView.Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source