Results 51 to 60 of about 25,814 (256)

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Determinantes dos pedidos estrangeiros de patentes dos países do G7 nos BRICS [PDF]

, 2009
TCC (graduação) - Universidade Federal de Santa Catarina. Centro Sócio-Econômico. Economia.Este estudo investiga os determinantes dos pedidos estrangeiros de patentes de origem no G7 (Alemanha, Canadá, Estados Unidos, França, Itália, Japão, Reino Unido ...
Bornschein, Francine Corrêa
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

O uso de patentes como fonte de informação em dissertações e teses de engenharia química: o caso da Unicamp / The use of patents as information source in chemical engineering dissertations and theses: the case of Unicamp

RDBCI: Revista Digital de Biblioteconomia e Ciência da Informação, 2010
Acredita-se que as patentes são pouco exploradas como documentos fornecedores de informações; tanto por empresas, quanto por instituições de pesquisa, universidades, etc.
Juliana de Paula Ravaschio, Leandro Innocentini Lopes de Faria, Luc Quoniam   +2 more
doaj  

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

FEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo, Kátia Cristiane Hall, Matheus dos Santos Fernandez, Geovanna Peter Corrêa, Rafael Guerra Lund   +4 more
wiley   +1 more source

Patentes em inteligência artificial: as mulheres inventoras brasileiras

Liinc em Revista
O estudo investiga a presença das mulheres no depósito de patentes prioritárias brasileiras em Inteligência Artificial. Se configura em um estudo patentométrico, com coleta de dados na base de dados do Instituto Nacional da Propriedade Industrial ...
Janaina Lais Pacheco Lara Morandin, Ana Maria Mielniczuk de Moura   +1 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Sistemas de patentes para fomentar la innovación: lecciones de análisis económico [PDF]

, 2010
La teoría económica, al considerar que las patentes son instrumentos de política pública para fomentar la innovación y la difusión de la tecnología, conduce principalmente a tres conclusiones.
Gellec, Dominique, Encaoua, David, Martínez, Catalina   +2 more
core  

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Patenteamento de tecnologias relacionadas a energias renováveis: o caso do biodiesel

Revista Tecnologia, 2010
Neste trabalho foi realizado um estudo de tendências tecnológicas sobre biodiesel com base em informações extraídas de documentos de patentes. O termo "documento de patente" abrange pedidos de patente publicados ou patentes concedidas.
Márcia França Fernandes dos Santos, Cristina Gomes de Souza, José Antônio Assunção Peixoto   +2 more
doaj