Results 131 to 140 of about 226,140 (260)
Patents, appropriate technology, and North-South trade [PDF]
In this paper, the authors discuss the possibility that the North and South may have differing technological needs. Just as the North would like to develop drugs against cancer and heart disease, and the South drugs against tropical disease, so the North'
Rodrik, Dani, Diwan, Ishac
core
Historical Trends in Intraocular Lens Innovation Through an Analysis of United States Patents, 1972-2000. [PDF]
Mason E, Lin T, Margo CE.
europepmc +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Linking science to technology: using bibliographic references in patents to build linkage schemes. [PDF]
In this paper, we develop and discuss a method to design a linkage scheme that links the systems of science and technology through the use of patent citation data.
Luwel, M +5 more
core
Current status of extracellular vesicle technology in industrialization and commercialization. [PDF]
Wu Y.
europepmc +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
A bibliometric analysis of the top 100 most-cited shoulder arthroscopy patents. [PDF]
Bhardwaj N +8 more
europepmc +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

