Results 171 to 180 of about 1,133,085 (338)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Fatal Steam Pop Complicating Investigational SESAME Transcatheter Myotomy Using Off-the-Shelf Equipment. [PDF]

Circ Cardiovasc Interv
Lederman RJ, Greenbaum AB, Halaby RN, Stine AM, Khan JM, Bruce CG, Rogers T, Gleason PT, Bilen O, Babaliaros VC.   +9 more
europepmc   +1 more source

Patente / Patents

Applied Rheology, 1996
openaire   +2 more sources

"Deep Pockets'', Collateral Assignments of Patents, and the Growth of Innovations [PDF]

This paper studies how the imperfect collateral assignments of patents contribute to "deep pockets'' savings of innovative firms facing random investment opportunities in research and development (R&D) and determine the growth of their innovations, using
Bruno Amable, Jean-Bernard Chatelain, Kirsten Ralf   +2 more
core  

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Summarizing relationships between chemicals, genes, proteins, and diseases in PubChem using analysis of their co-occurrences in patents. [PDF]

J Cheminform
Zaslavsky L, Cheng T, Gindulyte A, Kim S, Thiessen PA, Bolton EE.   +5 more
europepmc   +1 more source

Patent Registration: Bone infection drug delivery system

, 2018
Aghazadeh, Hamed, Mohammadiounotikandi, Ali, Mostafa, Shamloue, Aboulhassanzadeh, Sobhan, Sangchooli, Tahereh   +4 more
openalex   +1 more source

Patents, Citations, and Innovations: A Window on the Knowledge Economy

, 2002
A. Jaffe, M. Trajtenberg
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

La llengua i les patents

Terminàlia, 2017
Mireia Curell i Aguilà
doaj