Results 71 to 80 of about 629,170 (258)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Brief of Law Professors as Amicus Curiae in Support of Respondent [PDF]
, 2003 Inventors lacking assurance of a market, or even the right to practice patented inventions, face considerable risk. Those who qualify for patents, in return for disclosure, receive only the assistance of the courts in excluding others from economic ...
Field, Thomas G., Jr +3 more
core +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Patent policy, patent pools, and the accumulation of claims in sequential innovation [PDF]
We present a dynamic model where the accumulation of patents generates an increasing number of claims on sequential innovation. We study the equilibrium innovation activity under three regimes: patents, no-patents and patent pools.
Gaston Llanes, Stefano Trento
core
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
How Basic is (Patented) University Research? The Case of GM Crops [PDF]
One of the main reasons for subsidising university research is the widespread belief that it generates proportionally more positive knowledge externalities than corporate research.
K. Rockett, M. Conti, P. Regibeau
core
Legal Issues: Lawsuit Threatens BlackBerry Shutdown [PDF]
, 2006 For over four years a dispute has raged between Research in Motion (RIM), the Ontario, Canada based manufacturer of the BlackBerry, and NTP, a Virginia company which holds several patents covering wireless e-mail technologies.
Pike, George H.
core +1 more source
Prediction of Emerging Technologies Based on Analysis of the U.S. Patent Citation Network
, 2013 The network of patents connected by citations is an evolving graph, which provides a representation of the innovation process. A patent citing another implies that the cited patent reflects a piece of previously existing knowledge that the citing patent ...
A. Hargadon +76 more
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source