Results 91 to 100 of about 150,615 (347)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

open access: yesFEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Experiments on domain adaptation for patent machine translation in the PLuTO project [PDF]

open access: yes, 2011
The PLUTO1 project (Patent Language Translations Online) aims to provide a rapid solution for the online retrieval and translation of patent documents through the integration of a number of existing state-of-the-art components provided by the project ...
Ceausu, Alexandru   +3 more
core  

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Who Owns Biological Diversity? A Brief Description of the Debate over the Rights to Biological Diversity in the North-South Context [PDF]

open access: yes, 2000
For a long time, the genetic resources and biological diversity of all types of living organisms on the Earth were considered the common heritage of all of humanity.
Baier, Alexandra, Tappeser, Beatrix
core  

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Mining digital identity insights: patent analysis using NLP

open access: yesEURASIP Journal on Information Security
The field of digital identity innovation has grown significantly over the last 30 years, with over 6000 technology patents registered worldwide. However, many questions remain about who controls and owns our digital identity and intellectual property and,
Matthew Comb, Andrew Martin
doaj   +1 more source

Refining the Measurement of Topic Similarities Through Bibliographic Coupling and LDA

open access: yesIEEE Access, 2019
Generally, two topics with vastly different terminology probably indicate different implied concepts. However, these topics themselves might share common references (bibliographic coupling), which suggest the underlying joint concept.
Omer Hanif   +3 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

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