Results 81 to 90 of about 54,686,464 (254)

The Dynamics of the Transfer and Renewal of Patents [PDF]

open access: yes
This paper explores a new dataset of transfers of patents recorded at the United States Patent and Trademark Office. The aim of the paper is twofold. First, a number of patterns are presented.
Carlos J. Serrano
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Renewal of Patents and Government Financing [PDF]

open access: yes
I apply a survival model to a detailed dataset of Swedish patents to estimate how different factors affect the likelihood of patent renewal. Since the owners know more about the patents than potential external financiers, there is a problem of asymmetric
Svensson, Roger
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The Economics of Pending Patents [PDF]

open access: yes
We provide a treatment of a number of questions pertaining to pending patents – a subject that has so-far mainly been discussed en-passant in the existing literature.
Johannes Koenen, Martin Peitz
core  

Business Method Patents, Innovation, and Policy [PDF]

open access: yes
The trickle of business method patents issued by the United States Patent Office became a flood after the State Street Bank decision in 1998. Many scholars, both legal and economic, have critiqued both the quality of these patents and the decision itself.
Bronwyn H. Hall
core   +2 more sources

Mining digital identity insights: patent analysis using NLP

open access: yesEURASIP Journal on Information Security
The field of digital identity innovation has grown significantly over the last 30 years, with over 6000 technology patents registered worldwide. However, many questions remain about who controls and owns our digital identity and intellectual property and,
Matthew Comb, Andrew Martin
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Defining Software Patents: A Research Field Guide [PDF]

open access: yes
What distinguishes a patent on a software innovation from patents on other kinds of innovations? While the question may appear esoteric at first glance, it is the crucial first step in any empirical study of software patents.
Layne-Farrar, Anne
core  

Research on Identification and Diffusion of Emerging Topics Based on Citation Network and RAG

open access: yesZhishi guanli luntan
[Purpose/Significance] Based on the combination of traditional topic models and large language models, as well as RAG-based large language model, this study designs the topic modeling method, analyzes the diffusion of emerging topics and non-emerging ...
Tang Xinyu, Chen Wei
doaj   +1 more source

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