Results 61 to 70 of about 19,050 (292)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Fabrication and Use of Organic Electrochemical Transistors for Sensing of Metabolites in Aqueous Media

open access: yesApplied Sciences, 2018
This review first recalls the basic functioning principles of organic electrochemical transistors (OECTs) then focuses on the transduction mechanisms applicable to OECTs.
Benoît Piro   +7 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Discover semantic topics in patents within a specific domain [PDF]

open access: greenJ. Web Eng., 2017
Wenxuan Ma   +4 more
openalex   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Effects of Language and Topic Size in Patent IR: An Empirical Study [PDF]

open access: yes, 2012
We revisit the effects that various characteristics of the topic documents have on the effectiveness of the systems for the task of finding prior art in the patent domain. In doing so, we provide the reader interested in approaching the domain a guide of the issues that need to be addressed in this context.
Florina Piroi, Mihai Lupu, Allan Hanbury
openaire   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Implementation of Research and Development Based on Patent Natural Ingredients and Potential Utilization of Tradition Medicine

open access: yesAsian Journal of Technology Management, 2016
The results of research and development based on natural ingredients for traditional medicines become an interesting topic to discuss at this point; it’s shown from increasing number in utilization.
Tommy Hendrix
doaj   +1 more source

Patent Analysis of the Critical Technology Network of Semiconductor Optical Amplifiers

open access: yesApplied Sciences, 2020
With the development of 5G, mobile communication, and optical communication technologies, semiconductor optical amplifiers (SOAs) have become an important research topic.
Shu-Hao Chang
doaj   +1 more source

Home - About - Disclaimer - Privacy