Results 221 to 230 of about 150,615 (347)

Analyzing the evolutionary trajectory of technological themes based on the BERTopic model: A case study in the field of artificial intelligence. [PDF]

PLoS One
Zheng X, Wu Q, Luo X, Lv K.
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Exploring Technological Evolution of Aied Field Using Topic Modelling and Link Prediction Analysis Based on Patent Data

Hüseyin Özçınar, Aylin Sabancı Bayramoğlu   +1 more
openalex   +2 more sources

Evolution of AI enabled healthcare systems using textual data with a pretrained BERT deep learning model. [PDF]

Sci Rep
Wang YJ, Choo WC, Ng KY, Bi R, Wang PW.
europepmc   +1 more source

Hidden Markov Model based on patent topic evolution.

Heng Yang (590400), Sheng Chen (21971), Xin Yang (104842)   +2 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

STInt: An integrated dataset covering science, technology and industry information in the pharmaceutical field. [PDF]

Sci Data
Xu S, Liu Z, An X.
europepmc   +1 more source

Topic Modeling of Palantir Patents and List of Palantir Contracts

, 2021
Andrew Iliadis, Amelia Acker
openalex   +1 more source

University research, intellectual property rights and European innovation systems. [PDF]

Verspagen, Bart
core   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source