Results 241 to 250 of about 157,262 (340)

PROTAC-PatentDB: A PROTAC Patent Compound Dataset. [PDF]

Sci Data
Cai H, Yao G, Shi Y, Zhang T, Hu Y.
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Mineral-Vitamin Complexes in Sheep Nutrition: Patent Analysis and Functional Evaluation for Pregnant Ewes and Lambs. [PDF]

Molecules
Baibatyrova S, Onerbayeva A, Sagyzbaev A, Kenzhebaev T, Mukatayeva Z, Kurmanbayeva I.   +5 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Dollars and dilemmas: lenacapavir's pricing, patents, and the path to affordability. [PDF]

Int J Equity Health
Adepoju VA, Abdulrahim A.
europepmc   +1 more source

The impact of patent activity on idiosyncratic volatility in U.S. pharmaceutical companies. [PDF]

PLoS One
Atilgan E, Türkmen Ceylan FB, Doruk ÖT, Ertuğrul HM, Barak AY.   +4 more
europepmc   +1 more source

TB vaccine development: monitoring international patent filings to anticipate access challenges. [PDF]

Front Public Health
Pignataro MF, Scopel CT, Bacigalupo ML, Frick M, Kondratyuk S, Chaves GC.   +5 more
europepmc   +1 more source

Editorial: Safety and efficacy of CRISPR/Cas-based genome editing tools: applications and considerations in cell and gene therapy. [PDF]

Front Immunol
Petri K, Ferrari S, Cianciotti BC.
europepmc   +1 more source

TRIPS flexibilities help change policy and practice to increase access to medicines: evidence from 2001 to 2024. [PDF]

BMJ Glob Health
Dunn M, 't Hoen E, Boulet P, Mara K, Perehudoff K.   +4 more
europepmc   +1 more source