Results 51 to 60 of about 147,683 (344)

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Infrared Drying Trends Applied to Fruit

open access: yesFrontiers in Sustainable Food Systems, 2021
Aims: This article seeks to identify the main products to which drying is applied, mainly by infrared, as well as the mathematical models used to evaluate a product.Background: The drying of agro-industrial products is a very important unitary operation ...
Jhon Wilder Zartha Sossa   +4 more
doaj   +1 more source

A study of query expansion methods for patent retrieval [PDF]

open access: yes, 2011
Patent retrieval is a recall-oriented search task where the objective is to find all possible relevant documents. Queries in patent retrieval are typically very long since they take the form of a patent claim or even a full patent application in the ...
Jones, Gareth J.F., Magdy, Walid
core  

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Relating patenting and peer-review publications: an extended perspective on the vascular health and risk management literature

open access: yesVascular Health and Risk Management, 2011
Hermann AM MuckeHM Pharma Consultancy, Vienna, AustriaPurpose: This investigation identifies patent applications published under the international Patent Convention Treaty between July 2010 and January 2011 in three significant fields of vascular risk ...
Mucke H
doaj  

Identifying the trends in wound-healing patents for successful investment strategies. [PDF]

open access: yesPLoS ONE, 2017
BACKGROUND:Recently, the need for rapid wound-healing has significantly increased because of the increasing number of patients who are diagnosed with diabetes and obesity.
Jae Ha Gwak, So Young Sohn
doaj   +1 more source

Towards an Intellectual Property Rights Strategy for Innovation in Europe [PDF]

open access: yes, 2009
On October 13, 2009 the Science and Technology Options Assessment Panel (STOA) together with Knowledge4Innovation/The Lisbon Forum, supported by Technopolis Consulting Group and TNO, organised a half-day workshop entitled ‘Towards an Intellectual ...
Radauer, Alfred, Rodriguez, Victor
core   +2 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Keeping Up To Date with IP News Services and Blogs: Drowning in a Sea Of Sameness? [PDF]

open access: yes, 2006
It seems like so many IP related Websites you visit invite you to join their free email list to keep you up to date. Sources span a wide spectrum including governmental organizations, non-governmental organizations, educational institutions, consulting ...
Cavicchi, Jon R.
core   +1 more source

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

open access: yesFEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji   +5 more
wiley   +1 more source

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