Results 171 to 180 of about 16,399 (267)

The Evolutionary Psychopathology of Human Pair-Bonding. [PDF]

Clin Neuropsychiatry
Abed R, John-Smith PS.
europepmc   +1 more source

Prenatal Exome Sequencing Identifies Dual Maternal‐Fetal Diagnosis of HbF Mission Bay, a Novel HBG2 Variant Associated With Methemoglobinemia, Hypoxia and Hemolytic Anemia

Prenatal Diagnosis, EarlyView.
ABSTRACT Prenatal exome sequencing (ES) can establish rare genetic diagnoses in a fetus but may also lead to occult genetic diagnosis in a biological parent. We present a case of dual fetal and maternal diagnosis by prenatal ES, in a fetus with unexplained anemia and in a pregnant patient with sickle cell disease (SCD) and recurrent unexplained hypoxia.
Matthew A. Shear, Billie Lianoglou, Ugur Hodoglugil, W. Patrick Devine, Ashutosh Lal, Juan Gonzalez, Teresa N. Sparks   +6 more
wiley   +1 more source

Application of Probabilistic Genotyping Software to Paternity Cases Involving Low-Template DNA. [PDF]

Genes (Basel)
Riem A, Chierto E, Bertolotto F, Parnigoni M, Aneli S, Robino C.   +5 more
europepmc   +1 more source

Attitudes Toward Prenatal Interventions in the Fanconi Anemia Community

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective In‐utero cell and gene therapies may offer prenatal treatment options for inherited diseases. Preclinical data suggests in‐utero (IU) hematopoietic stem cell transplantation (HSCT) could prevent Fanconi anemia (FA) related bone marrow failure without genotoxic conditioning or immune suppression.
Tony Lum, Catherine Lee, Tippi MacKenzie, Billie Lianoglou, Agnieszka Czechowicz   +4 more
wiley   +1 more source

Genetic variation of 15 autosomal STR loci in the southern region population of KSA: A forensic DNA analysis study. [PDF]

J Taibah Univ Med Sci
Alhatim H, Muthanna A, Hakim Abdullah MN, Mohd Desa MN.   +3 more
europepmc   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Genetic profiling enhances cystic fibrosis prenatal diagnosis. [PDF]

Sci Rep
Hosseini Nami A, Kabiri M, Zafarghandi Motlagh F, Zeinali R, Karimi A, Aslani S, Zeinali S.   +6 more
europepmc   +1 more source

Scientific objectivity and social mores: Paternity testing, illegitimacy and misogyny in Constance Pascal's 'La Goutte de Sang' (1935-1936). [PDF]

Hist Psychiatry
Gordon F.
europepmc   +1 more source

Selective Paternalism

AMA Journal of Ethics, 2012
Brian C, Drolet, Candace L, White
openaire   +2 more sources

Structural Variation Sequencing of 26 Amniotic Fluid Samples With Partial Gene Duplications and Postnatal Follow‐Up of the Fetuses

Prenatal Diagnosis, EarlyView.
ABSTRACT Objectives Partial gene duplications (PGDups) are a significant contributor to genetic disease. The precise genomic location and structure of PGDups are often unresolved using conventional methods, so prenatal diagnosis for PGDups is challenging, especially without ultrasound abnormalities.
Shengfang Qin, Xueyan Wang, Mengjia Yan, Yuxia He, Zhuo Zhang, Yan Yin, Jin Wang, Beibei Guo, Jing Wang, Na Xi, Zhaokai Li   +10 more
wiley   +1 more source