Results 51 to 60 of about 1,024,245 (290)

One-way quantum computing in superconducting circuits

, 2018
We propose a method for the implementation of one-way quantum computing in superconducting circuits. Measurement-based quantum computing is a universal quantum computation paradigm in which an initial cluster-state provides the quantum resource, while ...
Albarrán-Arriagada, F., Alvarado-Barrios, G., Lamata, L., Retamal, J. C., Romero, G., Sanz, M., Solano, E.   +6 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Memristive Crossbar Arrays for Storage and Computing Applications

Advanced Intelligent Systems, 2021
The emergence of memristors with potential applications in data storage and artificial intelligence has attracted wide attentions. Memristors are assembled in crossbar arrays with data bits encoded by the resistance of individual cells.
Huihan Li, Shaocong Wang, Xumeng Zhang, Wei Wang, Rui Yang, Zhong Sun, Wanxiang Feng, Peng Lin, Zhongrui Wang, Linfeng Sun, Yugui Yao   +10 more
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

When the path is never shortest: a reality check on shortest path biocomputation

, 2017
Shortest path problems are a touchstone for evaluating the computing performance and functional range of novel computing substrates. Much has been published in recent years regarding the use of biocomputers to solve minimal path problems such as route ...
A Adamatzky, A Adamatzky, A Adamatzky, A. Tero, Andrew Adamatzky, C Scherber, CD Harvey, CR Reid, IH Riedel-Kruse, J Baumgardner, J Houten Van, J Houten Van, J Jones, Jeff Jones, K Ramsch, K Vittori, L Zhu, M Dorigo, M Vela-Pérez, Michael Esau, R Mayne, R Mayne, R Mayne, Richard Mayne, S Stepney, Saikat Jana, SC Pratt, T Hennessey, T Nakagaki   +28 more
core   +1 more source

A simple scheme for expanding photonic cluster states for quantum information [PDF]

, 2010
We show how an entangled cluster state encoded in the polarization of single photons can be straightforwardly expanded by deterministically entangling additional qubits encoded in the path degree of freedom of the constituent photons.
A. Laing, A. Stefanov, Chen, G. Mendoza, J. Coggins, J. L. O’Brien, Joo, Kiesel, Knill, Lu, M. Callaway, Marshall, Matthews, Nielsen, O’Brien, P. Kalasuwan, Park, Politi, Prevedel, Ralph, Raussendorf, S. Takeuchi, T. Nagata, Tokunaga, Vallone, Walther, Yoran   +26 more
core   +3 more sources

A neural network for shortest path computation [PDF]

IEEE Transactions on Neural Networks, 2001
This paper presents a new neural network to solve the shortest path problem for inter-network routing. The proposed solution extends the traditional single-layer recurrent Hopfield architecture introducing a two-layer architecture that automatically guarantees an entire set of constraints held by any valid solution to the shortest path problem.
F. Araújo, B. Ribeiro, L. Rodrigues
openaire   +3 more sources

Computational paths - a weak groupoid

Journal of Logic and Computation, 2023
Abstract On the basis of a labelled deduction system (LND$_{ED-}$TRS), we demonstrate how to formalize the concept of computational paths (sequences of rewrites) as equalities between two terms of the same type. This has allowed us to carry out a formal counterpart to equality between paths which is dealt with in homotopy theory, but ...
Tiago M L de Veras, Arthur F Ramos, Ruy J G B de Queiroz, Anjolina G de Oliveira   +3 more
openaire   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Efficient implicit simulation for incremental forming [PDF]

, 2010
Single Point Incremental Forming (SPIF) is a displacement controlled process performed on a CNC machine. A clamped blank is deformed by the movement of a small sized tool that follows a prescribed tool path.
Boogaard, A.H. van den, Hadoush, A.
core   +1 more source