Results 61 to 70 of about 98,734 (264)
Protocol for quantifying miRNA trafficking across the endosomal membrane
FEBS Open Bio, EarlyView.An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Extending SQL for Computing Shortest Paths [PDF]
Proceedings of the Fifth International Workshop on Graph Data-management Experiences & Systems, 2017 Reachability and shortest paths are among two of the most common queries realized on graphs. While graph frameworks and property graph databases provide an extensive and convenient built-in support for these operations, it is still both clunky and inefficient to perform on standard SQL DBMSs.
D. De Leo (Dean), P.A. Boncz (Peter)
openaire +2 more sources
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source
A Global Path Planning Algorithm Based on Bidirectional SVGA
Journal of Robotics, 2017 For path planning algorithms based on visibility graph, constructing a visibility graph is very time-consuming. To reduce the computing time of visibility graph construction, this paper proposes a novel global path planning algorithm, bidirectional SVGA (
Taizhi Lv, Chunxia Zhao, Jiancheng Bao
doaj +1 more source
A neural network for shortest path computation [PDF]
IEEE Transactions on Neural Networks, 2001 This paper presents a new neural network to solve the shortest path problem for inter-network routing. The proposed solution extends the traditional single-layer recurrent Hopfield architecture introducing a two-layer architecture that automatically guarantees an entire set of constraints held by any valid solution to the shortest path problem.
Filipe Araújo +2 more
openaire +3 more sources
Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen +6 more
wiley +1 more source
Constrained Shortest Path Computation
, 2005 This paper proposes and solves a-autonomy and k-stops shortest path problems in large spatial databases. Given a source s and a destination d, an a-autonomy query retrieves a sequence of data points connecting s and d, such that the distance between any two consecutive points in the path is not greater than a.
Manolis Terrovitis +3 more
openaire +3 more sources
Shortest path computation with no information leakage [PDF]
Proceedings of the VLDB Endowment, 2012 Shortest path computation is one of the most common queries in location-based services (LBSs). Although particularly useful, such queries raise serious privacy concerns. Exposing to a (potentially untrusted) LBS the client's position and her destination may reveal personal information, such as social habits, health condition, shopping preferences ...
Kyriakos Mouratidis, Man Lung Yiu
openaire +3 more sources
Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong +10 more
wiley +1 more source
High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis
Arthritis Care &Research, EarlyView.Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello +5 more
wiley +1 more source