Results 61 to 70 of about 118,666 (308)
Applied Sciences, 2022 Recent years have witnessed a paradigm shift from centralized cloud computing to decentralized edge computing. As a key enabler technique in edge computing, computation offloading migrates computation-intensive tasks from resource-limited devices to ...
Bo Xu +5 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2004 The advancement in the utilization and technologies of the Internet has led to the rapid growth of grid computing; and the perpetuating demand for grid computing resources calls for an incentive-compatible solution to the imminent QoS problem. This paper
Lin, M +5 more
core +1 more source
A neural network for shortest path computation [PDF]
IEEE Transactions on Neural Networks, 2001 This paper presents a new neural network to solve the shortest path problem for inter-network routing. The proposed solution extends the traditional single-layer recurrent Hopfield architecture introducing a two-layer architecture that automatically guarantees an entire set of constraints held by any valid solution to the shortest path problem.
Filipe Araújo +2 more
openaire +3 more sources
Computing and Listing Avoidable Vertices and Paths
Algorithmica, 2022 AbstractA simplicial vertex of a graph is a vertex whose neighborhood is a clique. It is known that listing all simplicial vertices can be done in O(nm) time or $$O(n^{\omega })$$ O ( n ω )
Charis Papadopoulos, Athanasios E. Zisis
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Shortest path computation with no information leakage [PDF]
Proceedings of the VLDB Endowment, 2012 Shortest path computation is one of the most common queries in location-based services (LBSs). Although particularly useful, such queries raise serious privacy concerns. Exposing to a (potentially untrusted) LBS the client's position and her destination may reveal personal information, such as social habits, health condition, shopping preferences ...
Kyriakos Mouratidis, Man Lung Yiu
openaire +3 more sources
Memristive Crossbar Arrays for Storage and Computing Applications
Advanced Intelligent Systems, 2021 The emergence of memristors with potential applications in data storage and artificial intelligence has attracted wide attentions. Memristors are assembled in crossbar arrays with data bits encoded by the resistance of individual cells.
Huihan Li +10 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source