Results 71 to 80 of about 2,647,850 (337)

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

Path Dependence or Path Creation? [PDF]

Journal of Management Studies, 2010
abstractWe discuss the assumptions that underlie path dependence, as defined by Vergne and Durand, and then provide the outlines of an alternative perspective which we label as path creation. Path creation entertains a notion of agency that is distributed and emergent through relational processes that constitute phenomena. Viewed from this perspective,
Garud, Raghu, Kumaraswamy, Arun, Karnøe, Peter   +2 more
openaire   +2 more sources

Implementing landslide path dependency in landslide susceptibility modelling

Landslides, 2018
Landslide susceptibility modelling—a crucial step towards the assessment of landslide hazard and risk—has hitherto not included the local, transient effects of previous landslides on susceptibility.
J. Samia, A. Temme, A. Bregt, J. Wallinga, J. Stuiver, F. Guzzetti, F. Ardizzone, M. Rossi   +7 more
semanticscholar   +1 more source

Dynamic Search-Space Pruning Techniques in Path Sensitization [PDF]

, 1994
— A powerful combinational path sensitization engine is required for the efficient implementation of tools for test pattern generation, timing analysis, and delay fault testing.
Marques-Silva, Joao, Sakallah, Karem
core   +2 more sources

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

Social History and Historical Sociology [PDF]

Historicka Sociologie, 2013
This paper deals with exchanges and misunderstandings between the German school of social history (most prominently represented by scholars from the University of Bielefeld (such as Hans-Ulrich Wehler) and Anglo-American trends in historical sociology ...
Wolfgang Knöbl
doaj  

Growing Green: the Role of Path Dependency and Structural Jumps in Green Economy Expansion

Journal on Policy and Complex Systems, 2019
Existing research argues that countries increase their production basket by adding products which require similar capabilities to those they already produce, a process referred to as path dependency.
Seyyedmilad Talebzadehhosseini, Steven R. Scheinert, I. Garibay   +2 more
semanticscholar   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Testing a Personalized Approach to Chronic Low Back Pain: A Randomized Controlled Trial in Older Veterans

Arthritis Care &Research, EarlyView.
Objective We aimed to test the efficacy of personalized treatment of older veterans with chronic low back pain (CLBP) delivered by Aging Back Clinics (ABCs) as compared with usual care (UC). Methods Two hundred ninety‐nine veterans aged 65 to 89 with CLBP from three Veterans Affairs (VA) medical centers underwent baseline testing, randomization to ABC ...
Debra K. Weiner, Angela Gentili, Meika A. Fang, Edward Garay, Laura Lawson, Lenore Joseph, Cathy C. Lee, Michelle I. Rossi, Beverly Thorn, Subashan Perera   +9 more
wiley   +1 more source

High Healthcare Utilization Preceding Diagnosis with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective Though early diagnosis improves long‐term outcomes, Juvenile Idiopathic Arthritis (JIA) patients often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize healthcare utilization in the year preceding diagnosis.
Anna Costello, Rui Xiao, Xuemei Zhang, Jahan Jazayeri, Irit R Rasooly, Pamela F Weiss   +5 more
wiley   +1 more source