Results 101 to 110 of about 2,978,757 (308)

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Statistical Gravity and Entropy of Spacetime

open access: yesStats
We discuss the foundations of the statistical gravity theory we proposed in a recent publication [Riccardo Fantoni, Quantum Reports, 6, 706 (2024)].
Riccardo Fantoni
doaj   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi   +19 more
wiley   +1 more source

A Gauge-Covariant Path-Integral Framework for the Aharonov–Bohm Effect: Topological Holonomy and Finite-Barrier Corrections

open access: yesMathematics
The Aharonov–Bohm (AB) effect demonstrates that a charged particle can acquire an observable phase shift in a region where the local magnetic field identically vanishes provided the configuration space is multiply connected and the electromagnetic ...
Luis Rojas-Valdivia   +2 more
doaj   +1 more source

An extended J-integral for evaluating fluid-driven cracks in hydraulic fracturing

open access: yesJournal of Rock Mechanics and Geotechnical Engineering, 2018
J-integral has served as a powerful tool in characterizing crack tip status. The main feature, i.e. path-independence, makes it one of the foremost fracture parameters.
Huifang Song, Sheik S. Rahman
doaj   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen   +6 more
wiley   +1 more source

Neural network representation of quantum systems

open access: yesMachine Learning: Science and Technology
It has been proposed that random wide neural networks near Gaussian process are quantum field theories around Gaussian fixed points. In this paper, we provide a novel map with which a wide class of quantum mechanical systems can be cast into the form of ...
Koji Hashimoto   +3 more
doaj   +1 more source

Nonperturbative Approach to the Description of Molecular Excitation by Ultrashort Laser Pulses

open access: yesEPJ Web of Conferences, 2015
We study the problem of excitation of molecules by an ultrashort laser pulse sequence by the use of path-integral approach in energy states space. Using numerical calculations of path-integral we evaluate laser field parameters at which there are quantum
Biryukov А.А., Shleenkov M.A.
doaj   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong   +10 more
wiley   +1 more source

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