Results 41 to 50 of about 4,121,276 (307)

Spatial representations of place cells in darkness are supported by path integration and border information

open access: yesFrontiers in Behavioral Neuroscience, 2014
Effective spatial navigation is enabled by reliable reference cues that derive from sensory information from the external environment, as well as from internal sources such as the vestibular system.
Sijie eZhang   +3 more
doaj   +1 more source

Towards a path dependence approach to study management innovation [PDF]

open access: yes, 2013
Purpose – Scholars in social sciences tend to use the term of path dependence without explaining exactly what they mean by it. Path dependence is a useful approach to understand the success or otherwise of the implementation of management innovation. The
Marin-Garcia, Juan A.   +3 more
core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Reference frames in virtual spatial navigation are viewpoint dependent

open access: yesFrontiers in Human Neuroscience, 2014
Spatial navigation in the mammalian brain relies on a cognitive map of the environment. Such cognitive maps enable us, for example, to take the optimal route from a given location to a known target.
Ágoston eTörök   +10 more
doaj   +1 more source

Principles of Insect Path Integration [PDF]

open access: yesCurrent Biology, 2018
Continuously monitoring its position in space relative to a goal is one of the most essential tasks for an animal that moves through its environment. Species as diverse as rats, bees, and crabs achieve this by integrating all changes of direction with the distance covered during their foraging trips, a process called path integration.
Heinze, Stanley   +2 more
openaire   +5 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Vestibular Loss in Older Adults Is Associated with Impaired Spatial Navigation: Data from the Triangle Completion Task

open access: yesFrontiers in Neurology, 2017
BackgroundVestibular inputs have been shown to play a critical role in spatial navigation. In this study, we sought to evaluate whether vestibular loss due to aging contributes to impaired spatial navigation as measured by the triangle completion task ...
Yanjun Xie   +5 more
doaj   +1 more source

Different Types of Survey-Based Environmental Representations: Egocentric vs. Allocentric Cognitive Maps

open access: yesBrain Sciences, 2023
The goal of the current study was to show the existence of distinct types of survey-based environmental representations, egocentric and allocentric, and provide experimental evidence that they are formed by different types of navigational strategies ...
Maria Kozhevnikov, Jyotika Puri
doaj   +1 more source

DISCRETIZATION OF THE SUPERPARTICLE PATH INTEGRAL [PDF]

open access: yesModern Physics Letters A, 1993
We investigate the hitherto unexplored relation between the superparticle path integral and superfield theory. Requiring that the path integral has the global symmetries of the classical action and obeys the natural composition property of path integrals, and also that the discretized action has the correct naive continuum limit, we find a viable ...
Grundberg, J.   +2 more
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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