Results 41 to 50 of about 16,963,565 (245)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Applicability study of the general wireless transmission path loss statistical model in mines

open access: yesGong-kuang zidonghua
Wireless network planning and optimization for systems such as mine mobile communication, personnel and vehicle positioning, wireless video transmission, and wireless sensing require link budget calculations to determine the maximum allowable wireless ...
PENG Ming
doaj   +1 more source

Ellipticity loss analysis for tangent moduli deduced from a large strain elastic–plastic self-consistent model [PDF]

open access: yes, 2009
In order to investigate the impact of microstructures and deformation mechanisms on the ductility of materials, the criterion first proposed by Rice is applied to elastic–plastic tangent moduli derived from a large strain micromechanical model combined ...
LORRAIN, Jean-Paul   +5 more
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Analysis of Downlink Uplink Decoupled Dense Heterogeneous Cellular Network based on User Association using Multi-Slope Path Loss Model

open access: yesAdvances in Electrical and Computer Engineering, 2019
Keeping in consideration the expected need of node densification of heterogeneous cellular networks in near future, it is imperative that more accurate path loss models be used when analyzing heterogeneous cellular networks performance in terms of user
ALI, S., ASLAM, M. I., AHMED. I., J.
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

An Automated Indoor Localization System for Online Bluetooth Signal Strength Modeling Using Visual-Inertial SLAM

open access: yesSensors, 2021
Indoor localization is becoming increasingly important but is not yet widespread because installing the necessary infrastructure is often time-consuming and labor-intensive, which drives up the price.
Simon Tomažič, Igor Škrjanc
doaj   +1 more source

Clipping Path Dhaka

open access: yes, 2023
Clipping Path Dhaka is a top-performing graphics design house, providing a wide range of professional services to clients all over the world. Our team is comprised of highly experienced experts, who have spent years mastering the art of Clipping Path ...
Clipping Path Clipping Path (16842768)
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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