Results 111 to 120 of about 1,726,520 (358)

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Developing a Coccidioides posadasii and SARS-CoV-2 Co-infection Model in the K18-hACE2 Transgenic Mouse

Communications Medicine
Background Early reports showed that patients with COVID-19 had recrudescence of previously resolved coccidioidomycosis (Valley fever, VF), and there were indications that coinfection had more severe outcomes.
Daniel R. Kollath, Francisca J. Grill, Ashley N. Itogawa, Ana Fabio-Braga, Matthew M. Morales, Kelly M. Shepardson, Mitchell L. Bryant, Jinhee Yi, Marieke L. Ramsey, Emily T. Luberto, Kimberly R. Celona, Paul S. Keim, Erik W. Settles, Douglas Lake, Bridget M. Barker   +14 more
doaj   +1 more source

Linkage in Linum Usitatissimum and in Melampsora Lini Between Genes Controlling Host-Pathogen Reactions [PDF]

, 1956
GME Mayo
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

A New Plating Medium for the Isolation of Enteric Pathogens [PDF]

, 1968
Sylvia King, William I. Metzger
openalex   +3 more sources

CHARACTERIZATION OF LEUKIN: AN ANTIBACTERIAL FACTOR FROM LEUCOCYTES ACTIVE AGAINST GRAM-POSITIVE PATHOGENS [PDF]

, 1956
Robert C. Skarnes, Dennis W. Watson
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

A Rapid Method for the Characterization of Enteric Pathogens Using Paper Discs [PDF]

, 1957
Arvey C Sanders, John E. Faber, Thomas M. Cook   +2 more
openalex   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Mechanisms underlying persistent liver fibrosis progression in Schistosoma-infected individuals post-treatment

Infectious Diseases of Poverty
Background Schistosomiasis, an infectious disease of poverty, remains a public health challenge worldwide. Although praziquantel chemotherapy has been proven to be an effective antiparasitic intervention, real-world evidence indicates that in patients ...
Zhigang Lei, Sha Zhou, Chuan Su, Guanling Wu   +3 more
doaj   +1 more source