Results 81 to 90 of about 1,638,877 (290)

Loop-mediated isothermal amplification (LAMP) assays targeting 18S ribosomal RNA genes for identifying P. vivax and P. ovale species and mitochondrial DNA for detecting the genus Plasmodium

Parasites & Vectors, 2021
Background Loop-mediated isothermal amplification (LAMP) has been widely used to diagnose various infectious diseases. Malaria is a globally distributed infectious disease attributed to parasites in the genus Plasmodium. It is known that persons infected
Xi Chen, Jiaqi Zhang, Maohua Pan, Yucheng Qin, Hui Zhao, Pien Qin, Qi Yang, Xinxin Li, Weilin Zeng, Zheng Xiang, Mengxi Duan, Xiaosong Li, Xun Wang, Dominique Mazier, Yanmei Zhang, Wei Zhao, Benjamin M. Rosenthal, Yaming Huang, Zhaoqing Yang   +18 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Diagnostics of dairy and beef cattle diarrhea. [PDF]

, 2012
Calf diarrhea is a multifactorial disease related to a combination of host and pathogen factors. The most common pathogens found in diarrheic calves are cryptosporidium, rotavirus, coronavirus, Salmonella, attaching and effacing E coli and F5 (K99 ...
Blanchard, Patricia Carey
core   +1 more source

Caraway yellows virus, a novel nepovirus from Carum carvi

Virology Journal, 2019
A novel nepovirus was identified and characterised from caraway, and tentatively named caraway yellows virus (CawYV). Tubular structures with isomeric virus particles typical for nepoviruses were observed in infected tissues by electron microscopy.
Yahya Z. A. Gaafar, Katja R. Richert-Pöggeler, Angelika Sieg-Müller, Petra Lüddecke, Kerstin Herz, Jonas Hartrick, Christina Maaß, Roswitha Ulrich, Heiko Ziebell   +8 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Genetic and phenotypic insights in the adaptation of Magnaporthe oryzae to rice. [PDF]

, 2015
Magnaporthe oryzae is the fungal pathogen causing rice blast. Rice resistance is commonly used to control this widely distributed and damaging disease of a major food crop.
Tharreau, Didier
core  

Fecal microbiota transplant rescues mice from human pathogen mediated sepsis by restoring systemic immunity. [PDF]

, 2020
Death due to sepsis remains a persistent threat to critically ill patients confined to the intensive care unit and is characterized by colonization with multi-drug-resistant healthcare-associated pathogens.
Alverdy, John C, Antonopoulos, Dionysios A, Barreiro, Luis B, Bouziat, Romain, Christley, Scott, DeFazio, Jennifer R, Ernest, Jordan D, Fleming, Irma D, Gilbert, Jack A, Harris, Katharine G, Hyoju, Sanjiv K, Jabri, Bana, Keskey, Robert, Khodarev, Nikolai N, Kim, Sangman M, Krezalek, Monika A, Malik, Ankit, Ranoa, Diana R, Sangani, Kishan, Sangwan, Naseer, Shakhsheer, Baddr A, Weichselbaum, Ralph R, Wiegerinck, Mara, Zaborin, Alexander, Zaborina, Olga   +24 more
core  

Non-systemic transmission of tick-borne diseases: a network approach [PDF]

, 2016
Tick-Borne diseases can be transmitted via non-systemic (NS) transmission. This occurs when tick gets the infection by co-feeding with infected ticks on the same host resulting in a direct pathogen transmission between the vectors, without infecting the ...
Bajardi, Paolo, Ferreri, Luca, Giacobini, Mario   +2 more
core   +2 more sources

Expression of microRNA-454 in TGF-β1-stimulated hepatic stellate cells and in mouse livers infected with Schistosoma japonicum

Parasites & Vectors, 2014
Background In the process of hepatic fibrosis, hepatic stellate cells (HSCs) can be activated by many inflammatory cytokines. The transforming growth factor-β1 (TGF-β1) is one of the main profibrogenic mediators.
Dandan Zhu, Xue He, Yinong Duan, Jinling Chen, Jianxin Wang, Xiaolei Sun, Hongyan Qian, Jinrong Feng, Wei Sun, Feifan Xu, Lingbo Zhang   +10 more
doaj   +1 more source

A divergent strain of melon chlorotic spot virus isolated from black medic (Medicago lupulina) in Austria

Virology Journal, 2019
A tenuivirus, referred to here as JKI 29327, was isolated from a black medic (Medicago lupulina) plant collected in Austria. The virus was mechanically transmitted to Nicotiana benthamiana, M. lupulina, M. sativa, Pisum sativum and Vicia faba.
Yahya Z. A. Gaafar, Katja R. Richert-Pöggeler, Angelika Sieg-Müller, Petra Lüddecke, Kerstin Herz, Jonas Hartrick, Yvonne Seide, Heinrich-Josef Vetten, Heiko Ziebell   +8 more
doaj   +1 more source