Inactivation of yellow fever virus with amotosalen and ultraviolet A light pathogen-reduction technology. [PDF]
Girard YA, Santa Maria F, Lanteri MC.
europepmc +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Comparative Efficiency of Mesophilic Anaerobic Digestion and Aerated Static Pile Composting in the Stabilization of Municipal Wastewater Sludge [PDF]
Introduction: Stabilization of municipal wastewater sludge is a critical requirement for mitigating environmental and public health risks. This study provides a comparative evaluation of mesophilic anaerobic digestion (AD) and aerated static pile (ASP ...
Mohammad Hasan Kowsari +5 more
doaj
Pathogen Reduction Technology: A Novel Possibility for Inactivation of Blood Products Used in Oral and Periodontal Surgeries. [PDF]
Varma SR +5 more
europepmc +1 more source
Computational investigation of pathogen evolution
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2015.Cataloged from PDF version of thesis.Includes bibliographical references (pages 105-118).Pathogen genomes, especially those of viruses,
Sealfon, Rachel (Rachel Sima)
core
Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin +11 more
wiley +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
This mini-review analyzed two approaches to screening bacterial contamination and utilizing pathogen reduction technology (PRT) for Platelet concentrates (PCs).
Mohammad Reza Rezvany +5 more
doaj +1 more source
Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova +9 more
wiley +1 more source
Background: The continued rise of antimicrobial resistance (AMR) and reduction of pharmacological options has created an urgent need for new countermeasures to prevent the spread of multidrug-resistant organisms (MDROs) (1). Infections caused by the MDRO
Kimberly Trosch +4 more
doaj +1 more source

