Results 261 to 270 of about 1,694,622 (312)
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Annals of Internal Medicine, 2003
Increased recognition of specific causes of hypertension may lead to therapies that address specific pathophysiologic mechanisms and cause fewer adverse effects.
Suzanne, Oparil +2 more
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Increased recognition of specific causes of hypertension may lead to therapies that address specific pathophysiologic mechanisms and cause fewer adverse effects.
Suzanne, Oparil +2 more
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Current Opinion in Infectious Diseases, 2013
Dengue is one of the most rapidly spreading vector-borne diseases in the world, with the incidence increasing 30-fold in the past 50 years. There are currently no licensed treatments or vaccines for dengue. This review covers the recent advances in our understanding of dengue pathogenesis, including host and viral determinants.The pathogenesis of ...
Sophie, Yacoub +2 more
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Dengue is one of the most rapidly spreading vector-borne diseases in the world, with the incidence increasing 30-fold in the past 50 years. There are currently no licensed treatments or vaccines for dengue. This review covers the recent advances in our understanding of dengue pathogenesis, including host and viral determinants.The pathogenesis of ...
Sophie, Yacoub +2 more
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2020
Osteoporosis is a condition where bone resorption exceeds bone formation leading to degeneration. With an aging population, the prevalence of osteoporosis is on the rise. Although advances in the field have made progress in targeting the mechanisms of the disease, the efficacy of current treatments remains limited and is complicated by unexpected side ...
Ahmed, Al Saedi +2 more
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Osteoporosis is a condition where bone resorption exceeds bone formation leading to degeneration. With an aging population, the prevalence of osteoporosis is on the rise. Although advances in the field have made progress in targeting the mechanisms of the disease, the efficacy of current treatments remains limited and is complicated by unexpected side ...
Ahmed, Al Saedi +2 more
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Pathogenesis of atherosclerosis
Maturitas, 1996Atherosclerosis is a disease which affects large and medium-sized arteries. Typical features of atherosclerosis are accumulation of intra- and extracellular lipids, foam cell formation, proliferation of smooth muscle cells and accumulation of connective tissue.
Ylä-Herttuala S +5 more
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The Pathogenesis of Hypercholesterolemia
Annals of Internal Medicine, 1974Abstract Elevation of serum cholesterol level is caused by decreased output and increased input. Increased input, as manifested by increased synthesis, seems to be the more common mechanism.
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Pathogenesis of steatohepatitis
Best Practice & Research Clinical Gastroenterology, 2002Understanding the pathogenesis of non-alcoholic steatohepatitis has recently assumed great importance with the recognition that it has the potential to progress to fibrosis and cirrhosis. The 'two-hit' model of pathogenesis was proposed in 1998, with the first 'hit' - steatosis - increasing the sensitivity of the liver to the second 'hits' mediating ...
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Current Opinion in Opthalmology, 1999
Pterygium is an active, invasive, inflammatory process, a key feature of which is focal limbal failure. In a two-stage process, "conjunctivalization" of the cornea occurs with tissue characterized by extensive chronic-inflammation, cellular proliferation, connective tissue remodeling, and angiogenesis.
M T, Coroneo +2 more
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Pterygium is an active, invasive, inflammatory process, a key feature of which is focal limbal failure. In a two-stage process, "conjunctivalization" of the cornea occurs with tissue characterized by extensive chronic-inflammation, cellular proliferation, connective tissue remodeling, and angiogenesis.
M T, Coroneo +2 more
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Science, 1994
Malaria is a disease caused by repeated cycles of growth of the parasite Plasmodium in the erythrocyte. Various cellular and molecular strategies allow the parasite to evade the human immune response for many cycles of parasite multiplication.
L H, Miller, M F, Good, G, Milon
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Malaria is a disease caused by repeated cycles of growth of the parasite Plasmodium in the erythrocyte. Various cellular and molecular strategies allow the parasite to evade the human immune response for many cycles of parasite multiplication.
L H, Miller, M F, Good, G, Milon
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Current Opinion in Virology, 2012
Measles is an important cause of childhood morbidity and mortality in developing countries. Measles virus (MV) is transmitted via the respiratory route and causes systemic disease. Over the last decade, identification of new cellular receptors and studies in animal models have challenged the historic concepts of measles pathogenesis. It is thought that
de Vries, Rory D. +4 more
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Measles is an important cause of childhood morbidity and mortality in developing countries. Measles virus (MV) is transmitted via the respiratory route and causes systemic disease. Over the last decade, identification of new cellular receptors and studies in animal models have challenged the historic concepts of measles pathogenesis. It is thought that
de Vries, Rory D. +4 more
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ON THE PATHOGENESIS OF CLUBFOOT
The Lancet, 1985Empirical testing has not revealed an indisputable cause of clubfoot. Evidence put forward for intrauterine moulding as a cause of idiopathic clubfoot does not stand up to scrutiny. The hypothesis that a regional growth disturbance is the cause of clubfoot would explain clinical and existing research data.
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