Results 211 to 220 of about 256,194 (269)

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

Before new variants in genes associated with hematuria or proteinuria can be classified as causative, their pathogenicity must be demonstrated. [PDF]

Kidney Res Clin Pract
Mehri S, Finsterer J.
europepmc   +1 more source

Beyond the gut microbe: Rethinking infection, microbiome harmony, and the one-health continuum. [PDF]

World J Gastrointest Pharmacol Ther
Rai S, Panda PK.
europepmc   +1 more source

A chromosome-level genome assembly of Thecaphora frezzii, cause of peanut smut, reveals the largest genome of the true smut fungi. [PDF]

G3 (Bethesda)
Greatens N, Couger MB, Maestro M, Walsh GC, Morichetti S, Tallon LJ, Bennett RS, Clevenger JP, Chamberlin KD, Koch Bach RA.   +9 more
europepmc   +1 more source

MoCul4 assists MoKmt1 to catalyze H3K9 methylation and regulates the growth, development, and pathogenicity in <i>Magnaporthe oryzae</i>. [PDF]

Virulence
Huang P, Xu C, Wang J, Zhang Y, Cao H, Wang J, Qiu H, Liu XH, Wang J, Lin FC, Lu J.   +10 more
europepmc   +1 more source

The Histone Demethylase JMJD2-Dependent Regulation of rDNA Transcription and Integrity of Nucleolus Is Required for Fungal Development and Pathogenicity in the Rice Blast Fungus. [PDF]

Mol Plant Pathol
Lee SH, Kim T, Lee JH, Park J, Kim KT, Son H, Jeon J.   +6 more
europepmc   +1 more source