Results 301 to 310 of about 573,776 (343)

First pathogenomic insights into Ganoderma ellipsoideum as an emerging causal agent of basal stem rot in oil palm. [PDF]

Sci Rep
Lakshmi MA, Bishnoi S, Ho CL, Tarafder E, Babu BK, Subbanna A, Sahu S, Palnam DW.   +7 more
europepmc   +1 more source

Decoding the Cellular Heterogeneity and Malignant Progression of Human Penile Squamous Cell Carcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
Single‐cell transcriptomic and functional analyses identify SEMA3C as a key regulator of tumor progression and tumor microenvironment remodeling in penile squamous cell carcinoma. SEMA3C promotes epithelial–mesenchymal transition, tumor growth, and invasion while shaping an immunosuppressive microenvironment, highlighting its potential as a prognostic ...
Xiheng Hu, Wensheng Shi, Liang Dong, Lingjuan Huang, Xiyuan Zhang, Yiting Feng, Jie Sun, Lanlan Liu, Teng Liu, Jun Fu, Bowen Zhong, Qihao Leng, Xiaohua Wu, Minfeng Chen, Lingfang Li, Yuan Li, Xin Jin, Long Wang, Jian Cao, Xin Li, Mingzhu Yin, Xiang Chen   +21 more
wiley   +1 more source

Evaluation of the Efficacy of Low-Concentration Gaseous Chlorine Dioxide in Inactivating Airborne H5 High Pathogenicity Avian Influenza Virus in Vivo Model. [PDF]

Food Environ Virol
Hew YL, Isoda N, Miura T, Hiono T, Sakoda Y.   +4 more
europepmc   +1 more source

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

Comparative analysis of pathogenicity and anticoccidial resistance of field-isolated <i>Eimeria</i> strains in Sichuan Province, China. [PDF]

Front Vet Sci
Zhang R, Li H, Wang X, Jike R, Lu S, Hao L.   +5 more
europepmc   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Systematic Identification of the Serine Protease Family (StSPs) and Functional Characterization of the Secretory Protein StSP8-4 for Pathogenicity in <i>Setosphaeria turcica</i>. [PDF]

Biology (Basel)
Zhou Q, Gong X, Zhang J, Zhou H, Zhu M, Hu B, Dong J, Liu Y, Gu S.   +8 more
europepmc   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

The Histone Acetyltransferase CgHat1 Regulates Growth, Development, and Pathogenicity of <i>Colletotrichum gloeosporioides</i>. [PDF]

J Fungi (Basel)
Jia B, Zhou Q, Liu Y, Chen Z, Liao M, Zhu C, Xiao C, Ai J.   +7 more
europepmc   +1 more source

The Aromatic Amino Acid Biosynthesis Gene <i>VdARO2</i> and the Cross-Pathway Regulator <i>VdCPC1</i> Coordinately Regulate Virulence in <i>Verticillium dahliae</i>. [PDF]

Microorganisms
Zhang C, Xu C, Wang Y, Huang J, Zhao X.
europepmc   +1 more source