Results 261 to 270 of about 1,804,540 (378)

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Fibroadhesive peritoneal tuberculosis mimicking inflammatory acute abdomen due to appendiceal adhesions

Revista de Gastroenterología de México (English Edition), 2017
P.C. González-Ferrer, Z.R. Romero-Amaro, M.V. Rivas-Castillo, P.A. Reyes-Duran, G.J. Arismendi-Morillo   +4 more
doaj   +1 more source

Extracellular volume fraction quantification by equilibrium contrast-enhanced CT via automated segmentation predicts survival outcomes in bladder cancer: a propensity score-matched study. [PDF]

Ann Med
Liu W, Guo Y, Gong B, Fu X, Lou J, Sun P, Li Y, Jiang S, Miao L, Pan F, Yang L.   +10 more
europepmc   +1 more source

THE PATHOLOGICAL DIAGNOSIS OF DISEASES OF THE APPENDIX BASED ON THE STUDY OF 1500 SPECIMENS

, 1916
Eli Moschcowitz
openalex   +2 more sources

ITGAV and SMAD4 influence the progression and clinical outcome of pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
In SMAD4‐positive pancreatic ductal adenocarcinoma (PDAC), integrin subunit alpha V (ITGAV) activates latent TGF‐β, which binds to the TGF‐β receptor and phosphorylates SMAD2/3. The activated SMAD2/3 forms a complex with SMAD4, and together they translocate to the nucleus, modulating gene expression to promote proliferation, migration, and invasion. In
Daniel K. C. Lee, Keyue Chen, Ryan Loke, Xiang Li, David Liubart, Golam T. Saffi, Jonathan T. S. Chow, Ché M. P. Melo, Lydia To, Leonardo Salmena   +9 more
wiley   +1 more source

Prophylactic oophorectomy is recommended in female patients with pseudomyxoma peritonei of an appendiceal origin. [PDF]

Front Oncol
Fu F, Ma X, Weng Z, Lu Y, Xu H, Ma R.
europepmc   +1 more source

A treatise on pathological anatomy [PDF]

William E. Horner
openalex   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

Pathology [PDF]

Postgraduate Medical Journal, 1943
openaire   +2 more sources

Impact of neoadjuvant therapy on cancer stem cell gene expression and miRNA profiles in breast cancer patients: Implications for therapy resistance and survival, a cross-sectional observational study. [PDF]

Medicine (Baltimore)
Kökenek Ünal TD, Kaplan Yilmaz MB, Kandemir O, Yora S, Taheri S.   +4 more
europepmc   +1 more source