DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial. [PDF]
Veliparib combined with carboplatin (VC) was an experimental regimen evaluated in the biomarker-rich neoadjuvant I-SPY 2 trial for breast cancer. VC showed improved efficacy in the triple negative signature.
Berry, Don+20 more
core +2 more sources
Gingival depigmentation: A split mouth comparative study between scalpel and cryosurgery
Gingival hyperpigmentation is a major esthetic concern for many people. Although it is not a medical problem, many people complain of dark gums as unesthetic.
Kaustubh P Patil+3 more
doaj +1 more source
African American men with low-grade prostate cancer have increased disease recurrence after prostatectomy compared with Caucasian men. [PDF]
PURPOSE: To explore whether disparities in outcomes exist between African American (AA) and Caucasian (CS) men with low-grade prostate cancer and similar cancer of the prostate risk assessment-postsurgery (CAPRA-S) features following prostatectomy (RP ...
Deville, Curtiland+9 more
core +2 more sources
Limb salvage procedure in occlusion of the infrapopliteal arteries [PDF]
Background/Aim. Limb salvage is a procedure for treatment of the causes of ischemia in the peripheral arteries of the lower limbs. This procedure consists of percutaneous transluminal angioplasty (PTA) of arteries of the infrapopliteal segment in the ...
Mijailović Milan, Lukić Snežana
doaj +1 more source
Genomic Classifier Augments the Role of Pathological Features in Identifying Optimal Candidates for Adjuvant Radiation Therapy in Patients With Prostate Cancer: Development and Internal Validation of a Multivariable Prognostic Model. [PDF]
Purpose Despite documented oncologic benefit, use of postoperative adjuvant radiotherapy (aRT) in patients with prostate cancer is still limited in the United States.
Abdollah, Firas+12 more
core +2 more sources
Endoscopic management of biliary complications after liver transplantation [PDF]
Objective: To retrospectively evaluate endoscopic treatmentoutcomes of biliary complications in post-liver transplants.Methods: The sample consisted of post-liver transplantationpatients referred to the Endoscopy Unit of Hospital Israelita AlbertEinstein,
Fernanda Prata Martins+2 more
doaj
Allodynia and hyperalgesia: review
The main purpose was to highlight the problem of hyperalgesia and allodynia. Main anatomic structures, which participate in nociception were mentioned in this article, with pathologic and pathophysiologic changes, that can be caused by hyperalgesia and ...
K. D. Dmytriiev+2 more
doaj +1 more source
Concomitant Carcinoma in situ in Cystectomy Specimens Is Not Associated with Clinical Outcomes after Surgery [PDF]
Objective: The aim of this study was to externally validate the prognostic value of concomitant urothelial carcinoma in situ (CIS) in radical cystectomy (RC) specimens using a large international cohort of bladder cancer patients. Methods: The records of
Colin P. Dinney+26 more
core +1 more source
Pathology and biobanking [PDF]
Biobanks are units where high quality and long-term protection of biomaterials is maintained. This system, in which biological materials and data are systematically recorded and stored, is a unique resource for the study of the pathophysiology of disease, the development of diagnostic biomarkers, and working with human tissues for the potential ...
Kelten Talu, Canan+3 more
openaire +5 more sources