Results 71 to 80 of about 747,735 (358)

Pathology Segmentation using Distributional Differences to Images of Healthy Origin [PDF]

In International MICCAI Brainlesion Workshop, pp. 228-238. Springer, Cham, 2018, 2018
Fully supervised segmentation methods require a large training cohort of already segmented images, providing information at the pixel level of each image. We present a method to automatically segment and model pathologies in medical images, trained solely on data labelled on the image level as either healthy or containing a visual defect.
arxiv   +1 more source

The multiple roles of the NlpC_P60 peptidase family in mycobacteria – an underexplored target for antimicrobial drug discovery

FEBS Letters, EarlyView.
The NlpC_P60 superfamily of peptidases is recognised by its key role in bacterial cell wall homeostasis. Recently, studies have also described the involvement of NlpC_P60‐like enzymes in bacterial competitive mechanisms and pathogenesis across several lineages.
Catharina dos Santos Silva, Marcio Vinicius Bertacine Dias   +1 more
wiley   +1 more source

Reconstrução cirúrgica da estenose cicatricial de vias biliares pós-colecistectomia

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Avaliar uma série de casos de estenose cicatricial de vias biliares pós-colecistectomia submetidos à reconstrução cirúrgica. MÉTODOS: Foi realizado estudo retrospectivo de 27 pacientes submetidos à reconstrução cirúrgica da via biliar por ...
Aderivaldo Coelho de Andrade
doaj   +1 more source

Unenhanced whole-body MRI versus PET-CT for the detection of prostate cancer metastases after primary treatment [PDF]

, 2016
The aim of this study was to evaluate the accuracy of unenhanced whole-body MRI, including whole-body Diffusion Weighted Imaging (DWI), used as a diagnostic modality to detect  pathologic lymph nodes and skeletal metastases in patients with prostate ...
AL ANSARI, Najwa, Barchetti, Flavio, Barchetti, Giovanni, Catalano, Carlo, Marini, Alessandra, Megna, Valentina, Monti, M. L, Musio, D, Panebianco, Valeria, Stagnitti, Andrea, Tombolini, Vincenzo   +10 more
core  

Development of an Ex Vivo Organ Culture Technique to Evaluate Probiotic Utilization in IBD [PDF]

, 2016
The consistent technical and conceptual progress in the study of the microbiota has led novel impulse to the research for therapeutical application of probiotic bacteria in human pathologies, such as inflammatory bowel disease (IBD).
DELLE FAVE, Gianfranco, Lanini, Claudio, Martorelli, M, Pagnini, C   +3 more
core   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

The Optimal Timing of Platelet-Rich Plasma (PRP) Injection for Nerve Lesion Recovery: A Preliminary Study

International Journal of Biomaterials, 2022
Introduction. Without appropriate treatment, nerve injuries may result in permanent loss of function. Platelet-rich plasma (PRP) injection is found to help in nerve regeneration.
Muhammad Pandunugrahadi, Komang Agung Irianto, Oen Sindrawati   +2 more
doaj   +1 more source

Clinical predictive factors of pathologic complete response in locally advanced rectal cancer [PDF]

, 2016
Background: Predictive factors of pathologic complete response (pCR) after neoadjuvant chemoradiotherapy (nCRT) in locally advanced rectal cancer (LARC) are still not identified. The purpose of this study was to define them. Materials and Methods: Data
Bulzonetti, Nadia, DE FELICE, Francesca, DI CELLO, Pierfrancesco, Izzo, Luciano, Izzo, Paolo, Izzo, Sara, Lucchetti, Pietro, Magnante Anna, Lisa, Musio, Daniela, Pugliese, Federico, Tombolini, Vincenzo   +10 more
core   +1 more source