Results 91 to 100 of about 1,072,961 (339)

Estenose idiopática de traquéia: relato de quatro casos Idiopathic tracheal stenosis: a report of four cases

open access: yesJornal Brasileiro de Pneumologia, 2007
A estenose idiopática de traquéia é incomum. Relatam-se quatro casos com quadro clínico semelhante: história de tratamento de broncoespasmo sem resultado e diagnóstico por broncoscopia. O tratamento em três pacientes foi dilatação e corticóide sistêmico;
Carolina Rossi   +4 more
doaj   +1 more source

Vorticity‐Facilitated Platelet Aggregation: a High Expansion‐Ratio Stenotic Microfluidic Platform Unravels the Role of Complex Flow Dynamics in Arterial Thrombosis

open access: yesAdvanced Healthcare Materials, EarlyView.
This study reveals how vorticity—a swirling flow pattern—enhances platelet aggregation and thrombus formation in high‐shear conditions. Using a custom microfluidic model, it is shows that vorticity promotes vWF–GPIbα interactions and calcium signaling, providing new insights into thrombosis mechanobiology and informing safer blood‐contacting medical ...
Jianfang Ren   +13 more
wiley   +1 more source

Progressive induction of left ventricular pressure overload in a large animal model elicits myocardial remodeling and a unique matrix signature [PDF]

open access: yes, 2012
ObjectivePatients with severe left ventricular pressure overload secondary to aortic stenosis can present with signs and symptoms of heart failure despite normal left ventricular ejection fraction.
Dixon, Jennifer A.   +9 more
core   +1 more source

Cardiac-specific Conditional Knockout of the 18-kDa Mitochondrial Translocator Protein Protects from Pressure Overload Induced Heart Failure. [PDF]

open access: yes, 2018
Heart failure (HF) is characterized by abnormal mitochondrial calcium (Ca2+) handling, energy failure and impaired mitophagy resulting in contractile dysfunction and myocyte death.
Bers, Donald M   +7 more
core   +2 more sources

Update on novel targets and potential treatment avenues in pulmonary hypertension.

open access: yesAmerican Journal of Physiology - Lung cellular and Molecular Physiology, 2016
Pulmonary hypertension (PH) is a condition marked by a combination of constriction and remodeling within the pulmonary vasculature. It remains a disease without a cure, as current treatments were developed with a focus on vasodilatory properties but do ...
J. Huetsch   +3 more
semanticscholar   +1 more source

Immunomodulation With Local, Sustained Delivery of Pituitary Adenylate Cyclase Activating Polypeptide Results in Improved Functional Recovery in Stroke‐Injured Mice

open access: yesAdvanced Healthcare Materials, EarlyView.
The tissue and functional benefits are demonstrated with local, sustained delivery of an anti‐inflammatory peptide, pituitary adenylate cyclase‐activating polypeptide (PACAP), for stroke treatment in a mouse model. Prolonged PACAP treatment modulated astrocyte and microglia toward pro‐reparative phenotypes, enhanced neuroprotection and preservation of ...
Eric Ho   +7 more
wiley   +1 more source

Evaluating the Epidemiology and Management of Bovine Congestive Heart Failure [PDF]

open access: yes, 2019
A form of congestive heart failure is increasingly reported as a cause of death in feedlot cattle located at moderate altitude (≤ 1524 m.). Significant knowledge gaps exist in the epidemiology and management of this form of bovine congestive heart ...
Bassett, Adam
core   +1 more source

CT and MRI imaging and interpretation of hepatic arterioportal shunts [PDF]

open access: yes, 2019
Hepatic arterioportal shunts (HAPS) occur due to organic or functional fistulization of blood flow between arterial hepatic vasculature and venous portal systems.
Akisik, Fatih   +7 more
core   +1 more source

Integration of Bioengineered Tools in Assisted Reproductive Technologies

open access: yesAdvanced Healthcare Materials, EarlyView.
A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak   +3 more
wiley   +1 more source

Cervical stenosis following electrosurgical conization

open access: yesSão Paulo Medical Journal
CONTEXT AND OBJECTIVE: Cervical stenosis is a postoperative complication of procedures for treating preinvasive lesions of the cervix and takes on particular importance due to the clinical repercussions associated with it.
Aparecida Cristina Sampaio Monteiro   +5 more
doaj   +1 more source

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