Results 101 to 110 of about 1,072,961 (339)

Acute modified Blalock-Taussing shunt obstruction successfully treated with urokinase and heparin [PDF]

, 2005
Acute modified Blalock-Tuassig shunt obstruction due to thrombosis may be lifethreatening. We report non-invasive relief of shunt obstruction with thrombolysis and heparinisation, a potentially life-saving intervention that is applicable in all ...
Grech, Victor E., Mizzi, Joseph
core   +1 more source

Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo

Advanced Materials, EarlyView.
Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll, Marc‐Joseph Antonini, Taylor M. Cannon, Pema Maretich, Greatness Olaitan, Valerie Doan Phi Van, Keisuke Nagao, Atharva Sahasrabudhe, Emmanuel Vargas Paniagua, Ethan J. Frey, Ye Ji Kim, Sydney Hunt, Melissa Hummel, Sanju Mupparaju, Alan Jasanoff, B. Jill Venton, Polina Anikeeva   +16 more
wiley   +1 more source

Effects of novel muscarinic M3 receptor ligand C1213 in pulmonary arterial hypertension models. [PDF]

, 2016
Pulmonary hypertension (PH) is a complex disease comprising a pathologic remodeling and thickening of the pulmonary vessels causing an after load on the right heart ventricle that can result in ventricular failure. Triggered by oxidative stress, episodes
Ahmed, Mohamed, Al-Abed, Yousef, Coleman, Thomas, Lakshminrusimha, Satyanarayana, Patel, Hardik, VanPatten, Sonya   +5 more
core   +2 more sources

Machine‐Learning‐Aided Advanced Electrochemical Biosensors

Advanced Materials, EarlyView.
Electrochemical biosensors are highly sensitive, portable, and versatile. Advanced nanomaterials enhance their performance, while machine learning (ML) improves data analysis, minimizes interference, and optimizes sensor design. Despite progress in both fields, their combined potential in diagnostics remains underexplored.
Andrei Bocan, Roozbeh Siavash Moakhar, Carolina del Real Mata, Max Petkun, Tristan De Iure‐Grimmel, Sripadh Guptha Yedire, Hamed Shieh, Arash Khorrami Jahromi, Sahar Sadat Mahshid, Sara Mahshid   +9 more
wiley   +1 more source

Videofluoroscopic swallow study abnormalities identify aerodigestive disorders in dogs with respiratory disease versus healthy controls

Journal of Veterinary Internal Medicine, 2023
Background Aerodigestive diseases (AeroD) pathologically link respiratory and alimentary tracts. Dogs with respiratory signs lacking dysphagia, vomiting, or regurgitation typically do not undergo diagnostic testing that identifies comorbid alimentary ...
Jennifer Howard, Megan Grobman, Teresa Lever, Carol R. Reinero   +3 more
doaj   +1 more source

Diagnostic and Therapeutic Approach in Intestinal Tuberculosis [PDF]

, 2016
Tuberculosis was still a global health problem. Beside lung, tuberculosis also manifest in other organs, one among them is in abdominal organs. Abdominal tuberculosis was a complex disease with unspecific sign and symptoms so that its diagnostic ...
Guno, T. H. (Tri), Kamelia, T. (Telly), Makmun, D. (Dadang), Putra, B. A. (Barry)   +3 more
core   +1 more source

HIF-driven SF3B1 induces KHK-C to enforce fructolysis and heart disease. [PDF]

, 2015
Fructose is a major component of dietary sugar and its overconsumption exacerbates key pathological features of metabolic syndrome. The central fructose-metabolising enzyme is ketohexokinase (KHK), which exists in two isoforms: KHK-A and KHK-C, generated
A Casonato, A Corrionero, A Hirschy, A Troilo, A Ventura, Alexandre Sarre, Ana Vukolic, AR Grosso, C Wang, CA Lewis, CJ David, CP Diggle, CP Diggle, Cédric Cortijo, Fiona Grimm, GL Semenza, GW Yip, H Dolatshad, H Kuroda, I Falcão-Pires, I Shiojima, J Fukuzawa, J Krishnan, J Krishnan, J König, J Rappsilber, JA Haefliger, JA Hill, Jaya Krishnan, Jernej Ule, JM Buescher, K-Y Kim, L van Heerebeek, LE Huang, M Fang, M Nemir, M Shiota, Manuel Hörl, Melis Kayikci, MG Vander Heiden, MG Vander Heiden, N-H Son, Nicola Zamboni, Niklaus Fankhauser, NL Barbosa-Morais, NS Radin, Owen Feehan, P Cirillo, Peter Mirtschink, R Koopman, R Ramasamy, S Bonnal, S Sharma, Samuel Sossalla, Sebastian N. Stehr, T Fuhrer, T Ishimoto, T Kawasaki, Thierry Pedrazzini, W Luo, WG Kaelin, Wilhelm Krek, Y Gao, Yann Christinat, Z Kassiri   +64 more
core   +2 more sources

Plaque‐Targeted Delivery of Fluoride‐Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy

Advanced Materials, EarlyView.
This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and anti­inflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai, Xinyue Lao, Sin‐Yi Pang, Yifei Zhao, Yuan Liu, Xiao Yu Tian, Jianhua Hao   +6 more
wiley   +1 more source

CTRP3 alleviates mitochondrial dysfunction and oxidative stress injury in pathological cardiac hypertrophy by activating UPRmt via the SIRT1/ATF5 axis

Cell Death Discovery
Pathological cardiac hypertrophy is an independent risk factor for heart failure. Disruption of mitochondrial protein homeostasis plays a key role in pathological cardiac hypertrophy; however, the mechanism of maintaining mitochondrial homeostasis in ...
Lei Shi, Yanzhen Tan, Wenying Zheng, Guojie Cao, Haitao Zhou, Panpan Li, Jun Cui, Yujie Song, Lele Feng, Hong Li, Wenju Shan, Bing Zhang, Wei Yi   +12 more
doaj   +1 more source

Topology in Biological Piezoelectric Materials

Advanced Materials, EarlyView.
This review summarizes the topological structures in biological piezoelectric materials, covering morphology evolution, spatial arrangement, and biomimetic strategies. These topologies modulate structure‐property relationships across multiple scales, enabling performance enhancement and multifunctional integration.
Chen Chen, Yanhu Zhang, Yi Zheng, Yi Zhang, Hongyi Liu, Jiang Wu, Liang Yang, Zhengbao Yang   +7 more
wiley   +1 more source