Results 141 to 150 of about 1,072,961 (339)
Gαq and its \u3ci\u3eAkt\u3c/i\u3eions [PDF]
No abstract ...
Eckhart, Andrea D.+2 more
core +1 more source
Integrated single‐cell transcriptomic and metabolomic analyses reveal that MYC‐driven glycolysis activates the PI3K‐AKT‐FOXO1 pathway, disrupting Th17/Treg balance and promoting uveitis. MYC inhibition restores immune homeostasis and alleviates disease symptoms.
He Li+11 more
wiley +1 more source
Radiological Society of North America (RSNA) 3D printing Special Interest Group (SIG): Guidelines for medical 3D printing and appropriateness for clinical scenarios [PDF]
Este número da revista Cadernos de Estudos Sociais estava em organização quando fomos colhidos pela morte do sociólogo Ernesto Laclau. Seu falecimento em 13 de abril de 2014 surpreendeu a todos, e particularmente ao editor Joanildo Burity, que foi seu ...
Ballard, David H, et al,
core +2 more sources
Organization of the Proteostasis Network of Membraneless Organelles
A comprehensive mapping of the proteostasis network (PN) across membraneless organelles (MLOs) reveals how central PN components coordinate MLO regulation. The analysis uncovers principles of specificity and promiscuity within the PN. The findings suggest that HSP70 chaperones act as generic MLO regulators, while client specific HSP70 co‐chaperones may
Christine M. Lim+6 more
wiley +1 more source
Lynch et al., identified novel targets on the wake‐promoting pathways that can effectively treat pain‐induced sleep disturbances. The authors demonstrated that Calcitonin gene‐related peptide‐expressing neurons (CGRP) in the external lateral parabrachial nucleus (PBelCGRP) serve as the primary relay node for pain stimuli that cause sleep disruption ...
Nicole Lynch+13 more
wiley +1 more source
Endoscopic management of biliary complications after liver transplantation [PDF]
Objective: To retrospectively evaluate endoscopic treatmentoutcomes of biliary complications in post-liver transplants.Methods: The sample consisted of post-liver transplantationpatients referred to the Endoscopy Unit of Hospital Israelita AlbertEinstein,
Fernanda Prata Martins+2 more
doaj
Correlation of periodontal pathogens in concurrent endodontic-periodontal diseases [PDF]
Objectives: This study investigated the correlation between Tannerella forsythia, Porphyromonas gingivalis, Fusobacterium nucleatum, and Aggregatibacter actinomycetemcomitans at dual sites in concurrent endodonticperiodontal diseases.
Bajrović, Kasim+5 more
core +1 more source
The Pathology of Congenital Ring Constrictions [PDF]
openaire +3 more sources
Advanced Microfluidics for Single Cell‐Based Cancer Research
Cutting‐edge microfluidic platforms are transforming single‐cell cancer research. This review highlights advanced technologies, from droplet microfluidics to tumour‐chips, that enable functional and spatial single‐cell analyses. By integrating biosensing, immune components, and patient‐derived materials, these systems offer new insights into tumour ...
Adriana Carneiro+10 more
wiley +1 more source
Generation of Neural Organoids and Their Application in Disease Modeling and Regenerative Medicine
Neural organoids provide a versatile platform for neurological research. Advances in organoid technology have partially achieved human neural tissue complexity in terms of tissue structure, cell diversity, and neural signaling, offering insights into neural disorders and regenerative strategies. Technology advances from biomaterials, bio‐manufacturing,
Ruiqi Huang+4 more
wiley +1 more source