Results 281 to 290 of about 1,072,961 (339)

Intrabolus pressure gradient identifies pathological constriction in the upper esophageal sphincter during flow [PDF]

open access: closedAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 2003
Propulsion of a bolus through the upper esophageal sphincter (UES) is driven by a pressure drop in the direction of flow against frictional resisting force. Basic mechanics suggest that the axial rate of drop in intrabolus pressure (IBP), i.e., the intrabolus pressure gradient (IBPG), should be locally sensitive to abnormal constriction.
Anupam Pal   +3 more
openalex   +3 more sources

Pathological Findings of Hourglass-Like Constriction in Spontaneous Posterior Interosseous Nerve Palsy

open access: closedThe Journal of Hand Surgery, 2020
We report the pathological findings of hourglass-like fascicular constriction (HLFC) under optical and electron microscopy. A 24-year-old man with spontaneous posterior interosseous nerve palsy was treated by interfascicular neurolysis at 29 weeks after onset.
Masatoshi Komatsu   +5 more
openalex   +4 more sources

Effect of sodium channel blocker (mexiletine) on pathological ectopic firing pattern in a rat chronic constriction nerve injury model

open access: closedJournal of Orthopaedic Science, 2005
We studied the efficacy of mexiletine as a sodium channel blocker for neuropathic pain by investigating the effect of mexiletine on the pathological ectopic firing pattern in a chronic constriction nerve injury (CCI) model. The experiment was conducted with 60 male Wistar rats. The CCI model was created by loosely ligating the sciatic nerve.
Satoru Nakamura, Yuji Atsuta
openalex   +4 more sources

Abstract 60: Cardiac-specific Deletion of HuR Reduces Pathological Hypertrophy and Ventricular Remodeling Following Transverse Aortic Constriction

open access: closedCirculation Research, 2015
The RNA binding protein HuR (Human antigen R) interacts with specific AU-rich domains in target mRNAs and is highly expressed in many cell types, including cardiomyocytes. However, the role of HuR in cardiac physiology is largely unknown. Our results show that HuR undergoes cytoplasmic translocation, indicative of its activation, in hypertrophic mouse ...
Michael Tranter   +6 more
openalex   +3 more sources

Melatonin protects against the pathological cardiac hypertrophy induced by transverse aortic constriction through activating PGC‐1β: In vivo and in vitro studies

open access: closedJournal of Pineal Research, 2017
AbstractMelatonin, a circadian molecule secreted by the pineal gland, confers a protective role against cardiac hypertrophy induced by hyperthyroidism, chronic hypoxia, and isoproterenol. However, its role against pressure overload‐induced cardiac hypertrophy and the underlying mechanisms remains elusive.
Mengen Zhai   +19 more
openalex   +4 more sources

Quantitative assessment of the occurrence of asymmetric and symmetrical maxillary constriction and related pathological conditions

open access: closedStomatology for All / International Dental review
Quantitative assessment of the occurrence of asymmetric and symmetrical maxillary constriction and related pathological ...
Kh. R. Khumgaeva   +3 more
openalex   +2 more sources

Chronic constrictive pericarditis: Further consideration of the pathologic physiology of the disease

American Heart Journal, 1952
Abstract 1. 1. The methods of catheterization of the heart and the pulmonary vessels make it practical, for the first time, to investigate the pressure and flow phenomena in the right side of the heart and in the pulmonary vascular system of patients with constrictive pericarditis. Six such patients have been studied by these methods. 2.
Eugene C. Eppinger   +7 more
openaire   +3 more sources

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