Results 91 to 100 of about 6,088 (212)

Macular telangiectasia type 2 genetic risk variants associated with clinical characteristics in the Slovenian cohort

Acta Ophthalmologica, EarlyView.
Abstract Purpose Early diagnosis of macular telangiectasia type 2 (MacTel) remains challenging, and the contribution of genetic variation to its clinical heterogeneity is unclear. This study investigated associations between MacTel risk variants and clinical characteristics in a Slovenian cohort.
Ajda Kunčič, Nataša Debeljak, Petra Hudler, Janez Smerkolj, Mojca Urbančič   +4 more
wiley   +1 more source

Explainable deep learning self‐supervised vision transformer for fundus‐based myopia classification

Acta Ophthalmologica, EarlyView.
Abstract Purpose To develop and validate a self‐supervised vision transformer (ViT) for automated three‐class classification of Normal, High Myopia (HM), and Pathologic Myopia (PM) from colour fundus photographs, with anatomically faithful interpretability. Methods A DINOv2 self‐supervised ViT was fine‐tuned using a two‐stage transfer‐learning protocol
Eirini Maliagkani, Christos Tsoutsas, Nikolaos Papageorgiou, Ioannis D. Apostolopoulos, Nikolaos Papandrianos, Ilias Georgalas, Elpiniki Papageorgiou   +6 more
wiley   +1 more source

Artificial intelligence prediction algorithms for refractive error onset and progression in children and adolescents: A systematic review and meta‐analysis

Acta Ophthalmologica, EarlyView.
Abstract This systematic review and meta‐analysis evaluates the performance of artificial intelligence (AI)‐based models for predicting the onset and progression of refractive error (RE) in children and adolescents and quantitatively synthesizes their prediction accuracy.
Athanasia Sandali, Anna Nikolaidou, Theodora Gianni, Andreas Katsimpris, Ioannis D. Apostolopoulos, Lampros Lamprogiannis, Eirini Maliagkani   +6 more
wiley   +1 more source

Systematic quantification of outer retinal morphology in three different SD‐OCT devices in geographic atrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To define interdevice differences in quantitative outer retinal biomarkers across three spectral‐domain (SD) optical coherence tomography (OCT) devices in geographic atrophy (GA). Methods Patients with GA prospectively underwent imaging using Spectralis (Heidelberg Engineering), Cirrus (Zeiss) and Maestro (Topcon) OCT devices ...
Klaudia Birner, Sophie Frank‐Publig, Julia Mai, Anna Eidenberger, Johannes Schrittwieser, Gabriel Leitner‐Barrios, Magdalena Barasits, Markus Gumpinger, Gregor S. Reiter, Stefan Sacu, Ursula Schmidt‐Erfurth   +10 more
wiley   +1 more source

Long-term outcomes of early posterior scleral contraction for myopic macular retinoschisis in patients up to 30 years

Frontiers in Medicine
AimTo evaluate the long-term anatomical and functional outcomes of early posterior scleral contraction (PSC) in patients up to 30 years with myopic macular retinoschisis (MRS).MethodsThis retrospective study included 21 patients (27 myopic eyes) with MRS,
Linyan Zheng, Linyan Zheng, Jian Zhao, Jian Zhao, Caiyu Yu, Caiyu Yu, Liang Dong, Liang Dong, Anquan Xue, Anquan Xue, Shuangqian Zhu, Shuangqian Zhu   +11 more
doaj   +1 more source

Proliferative vitreoretinopathy: An integrative, multi‐pathway perspective on pathogenesis and therapy

Acta Ophthalmologica, EarlyView.
Abstract Proliferative vitreoretinopathy (PVR) remains the principal biological cause of failed retinal detachment repair. Classical pathogenic models centred on retinal pigment epithelium (RPE) dispersion, retinal injury responses or compartment‐restricted mechanisms do not fully explain the heterogeneity, biomechanical behaviour and clinical ...
Koen A. van Overdam, J. Sebag
wiley   +1 more source

Optic nerve head blood flow autoregulation during isometric exercise in primary open‐angle glaucoma assessed by laser speckle flowgraphy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess optic nerve head blood flow (ONHBF) autoregulation in patients with early‐ to moderate‐stage primary open‐angle glaucoma (POAG) and age‐ and sex‐matched healthy controls using laser speckle flowgraphy (LSFG) and isometric handgrip exercise.
Theresa Lindner, Viktoria Pai, Patrick Janku, Nikolaus Hommer, Anton Hommer, Liudmyla Petric, Ulrich Graf, Leopold Schmetterer, Gerhard Garhöfer, Doreen Schmidl   +9 more
wiley   +1 more source

Screen Time Exposure and Children's and Adolescents' Health. A Position Paper from the European Academy of Paediatrics (EAP) and European Confederation of Primary Care Paediatricians (ECPCP)

Acta Paediatrica, EarlyView.
ABSTRACT Aim This position paper aims to synthesize current evidence on the effects of screen exposure on children's and adolescents' physical, mental and social health, critically review existing international and European guidelines, and propose coordinated, harmonized and age‐appropriate recommendations for policymakers, paediatric societies ...
Lorenza Onorati, Grigorios Papantoniou, Berthold Koletzko, Artur Mazur, Dominique Kyriaki Karafyllidou, Eugenio Baraldi, Laura Reali   +6 more
wiley   +1 more source

Clinical Profile of posterior segment in high Myopia

Journal of Nepal Health Research Council
Background: Myopia is a growing global health concern, with prevalence surging, especially in East and Southeast Asia. The World Health Organization identifies high myopia as -5.00 diopter or less, carrying an elevated risk of irreversible blindness. In
Raju Kaiti, Birkha Bogati, Ranjila Shyangbo, Simanta Khadka, Priya Bajgai   +4 more
doaj   +1 more source

Premium Intraocular Lens Selection in Patients With Glaucoma: A Clinical Review

Clinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Glaucoma frequently coexists with cataract, but glaucomatous functional loss, ocular‐surface disease, anatomical abnormalities, and treatment‐related refractive variability may reduce tolerance of premium intraocular lenses. This narrative review critically appraises evidence relevant to lens selection in glaucoma. Central visual‐field status,
Zhihao Liu, Yajuan Zheng, Mingxuan Wang, Jing Zhao   +3 more
wiley   +1 more source