Results 121 to 130 of about 2,638,293 (327)

Scaling and Eigenmode Tests of the Improved Fat Clover Action

, 2000
We test a recently proposed improved lattice-fermion action, the fat link clover action, examining indicators of pathological small-quark-mass lattice artifacts ("exceptional configurations") on quenched lattices of spacing 0.12 fm and studying scaling ...
A. Hasenfratz, Anna Hasenfratz, C. Bernard, Carleton DeTar, D. B. Kaplan, D. B. Kaplan, G. Bali, G. P. LePage, K. Bitar, M. Albanese, M. Falcioni, M. Fukugita, M. Gockeler, M. Lüscher, Mark Stephenson, R. G. Edwards, R. G. Edwards, R. Narayanan, R. Narayanan, R. Narayanan, R. Narayanan, S. Aoki, T. DeGrand, T. DeGrand, T. DeGrand, T. DeGrand, Thomas DeGrand, V. Furman, W. Bardeen, W. Bardeen, W. Bardeen, Y. Iwasaki, Y. Kuramashi, Y. Shamir   +33 more
core   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

THE CYCLIC CHANGES IN THE MAMMARY GLAND UNDER NORMAL AND PATHOLOGICAL CONDITIONS [PDF]

, 1917
Leo Loeb, Cora Hesselberg
openalex   +1 more source

Application of the Sensory Contact Model for Pharmacological Studies under Simulated Clinical Conditions [PDF]

, 2007
The sensory contact model allows forming different psycho-pathological states (anxious depression, catalepsy, social withdrawal, pathological aggression, cognition disturbances, anhedonia, addictive states etc.) produced by repeated agonistic ...
Damira F. Avgustinovich, Irina L. Kovalenko, Michael V. Tenditnik, Natalia N. Kudryavtseva, Natalia P. Bondar   +4 more
core   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Correlation of Certain Bronchographic Abnormalities Seen in Chronic Bronchitis with the Pathological Changes [PDF]

, 1955
Lynne Reid
openalex   +1 more source

Estimation of Severity of Speech Disability through Speech Envelope

, 2011
In this paper, envelope detection of speech is discussed to distinguish the pathological cases of speech disabled children. The speech signal samples of children of age between five to eight years are considered for the present study.
Gudi, Anandthirtha B., Nagaraj, H. C., Shreedhar, H. K.   +2 more
core   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

THE CLINICAL PICTURE OF MULTIPLE SCLEROSIS WITH THE PATHOLOGICAL FINDINGS OF ARTERIOSCLEROSIS [PDF]

, 1909
CHARLES K. MILLS, WILLIAM G. SPILLER
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source