Results 101 to 110 of about 1,606,417 (371)
Exercise Volume Can Modulate the Regenerative Response to Spinal Cord Injury in Mice
Neurotrauma ReportsTraumatic spinal cord injury (SCI) causes debilitating motor and sensory deficits that impair functional performance, and physical rehabilitation is currently the only established therapeutic reality in the clinical setting.
Anne Caroline Rodrigues dos Santos +6 more
doaj +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
The Jefferson Medical College of Philadelphia: From 1825 to 1908 [PDF]
, 1908 This brief 1908 history of Jefferson Medical College was written by James W. Holland. An 1868 graduate, Holland went on to become the Dean of Jefferson Medical College in 1887https://jdc.jefferson.edu/jeffersonhistorybooks/1007/thumbnail ...
Holland, James W.
core +1 more source
Scientific Method for Medical Practitioners: The Case Method of Teaching Pathology in Early Twentieth-Century Edinburgh [PDF]
, 2007 The appointment of James Lorrain Smith as first full-time professorof pathology at the University of Edinburgh in 1912 led to a series of reformsin pathology teaching there.
Sturdy, Steven
core +1 more source
Low Ki-67 gene expression in non-neoplastic proliferation of oral mucosal epithelium [PDF]
Universa Medicina, 2012 Background Neoplastic and non-neoplastic oral mucosal growths often have a variety of clinical manifestations according to their biological nature.
Janti Sudiono, Irmawati Hassan
doaj
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Molecular Oncology, EarlyView.Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
RAGE Signaling in Skeletal Biology [PDF]
, 2019 PURPOSE OF REVIEW: The receptor for advanced glycation end products (RAGE) and several of its ligands have been implicated in the onset and progression of pathologies associated with aging, chronic inflammation, and cellular stress. In particular, the
Davis, Hannah M. +2 more
core +2 more sources
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source