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Pediatric malignant testicular germ cell tumors: a developmental and comparative perspective [PDF]

Diagnostic Pathology
Malignant testicular germ cell tumors exhibit significant histologic diversity, particularly across pediatric age groups. Prepubertal patients more commonly develop yolk sac tumors, whereas postpubertal adolescents are more likely to present with mixed ...
Sonja Chen, Andres Matoso
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PD-L1 expression in testicular germ cell tumors undergoing spontaneous regression [PDF]

Biomolecules & Biomedicine
Spontaneous regression of testicular germ cell tumors is a well-known phenomenon; however, the precise mechanisms of spontaneous regression are still unknown.
Ivan Novak, Miroslav Tomić, Denis Mulabdić, Ivan Pezelj, Slaven Čiček, Igor Tomašković, Nino Sinčić, Božo Krušlin, Monika Ulamec   +8 more
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The value of contrast-enhanced ultrasonography in differential diagnosis of primary testicular germ cell tumors and non-germ cell tumors over 50 years old

Frontiers in Oncology, 2023
BackgroundUnlike young and middle-aged patients, seminoma is not common in patients with primary testicular tumors over the age of 50, so it cannot follow the general ideas and norms for diagnosing and treating testicular tumors, and its characteristics ...
Nianyu Xue, Guoyao Wang, Shengmin Zhang, Yijun Lu   +3 more
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Lost in descent: Complications of cryptorchidism

Radiology Case Reports, 2023
Cryptorchidism is a relatively common and important clinical entity and can lead to an array of downstream complications if it is not corrected in a timely manner, most notably with the development of testicular germ cell tumors.
Lauren Facer, MD, Theresa Pham, MD, Douglas Rogers, MD   +2 more
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Familial testicular germ cell tumors in two brothers

IJU Case Reports, 2020
Introduction Two percent of testicular germ cell tumors occur in family clusters. Here, we report metachronous testicular germ cell tumors in two brothers.
Senji Hoshi, Vladimir Bilim, Kiyotsugu Hoshi, Isoji Sasagawa, Kotarou Otake, Daigo Chiba, Shinta Suenaga, Masahito Konno, Yuki Katsumata, Kento Morozumi, Jun Takemoto, Kenji Numahata, Keiichi Ito   +12 more
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Testicular cancer metastasis to the soft tissue: A case report and review of the literature

Radiology Case Reports, 2021
While germ cell testicular cancer is rare and only accounts for 1% of cancers in males, it is the most common solid malignancy among men between 14 and 44 years of age.
Matthew A. Crain, BS, Dhairya A. Lakhani, MD, Aneri B. Balar, MD, Daniel Martin, MD, Cara B Lombard, MD, Thuan-Phuong Nguyen, MD   +5 more
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Retroperitoneal germ cell tumor, primary or secondary: A diagnostic conundrum

MGM Journal of Medical Sciences, 2023
Germ cell tumor, seminoma, is the most common cancer in young men’s testis. However, a small subset of tumors (1%–2%) originate in other locations and are referred to as primary extragonadal germ cell tumors. But such type of tumors’ origin is thought to
Surabhi Singh, Pranita Mohanty, Prateek Das, Debahuti Mohapatra, Pradyumna Kumar Sahoo   +4 more
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Exploring the microbiome-gut-testis axis in testicular germ cell tumors [PDF]

Frontiers in Cellular and Infection Microbiology
Michal Mego, Sona Ciernikova, Aneta Ševčíková   +2 more
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Seminoma metastasized to the prostate: A case report and literature review

Urology Case Reports, 2020
The testicular seminomas are germ-cell tumors which account for approximately 50% of all testicular tumors. Most primary testicular germ cell tumors metastasize through a lymphatic system in a predictable pattern with the retroperitoneal lymph nodes ...
Ceren Durer, Isin Yagmur Comba, Seren Durer, Nancy Torres Luna, Parikh Jignesh, Allison Carilli   +5 more
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Surgical resection in patient with teratoma with somatic‐type malignancy transformed into rhabdomyosarcoma resulted in long‐term survival

IJU Case Reports, 2023
Introduction Testicular germ cell tumors with somatic‐type malignancy, wherein teratomas transform into sarcomas, is drug resistant and has a poor prognosis.
Junji Kitamura, Mitsuhiro Tambo, Ayano Nishijima, Kazuki Masuda, Jimpei Miyakawa, Yu Nakamura, Masachika Fujiwara, Takeshi Kishida, Hiroyuki Ito, Hiroshi Fukuhara   +9 more
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