Effect of FSH on testicular morphology and spermatogenesis in gonadotrophin-deficient hypogonadal mice lacking androgen receptors [PDF]
Follicle stimulating hormone (FSH) and androgen act to stimulate and maintain spermatogenesis. FSH acts directly on the Sertoli cells to stimulate germ cell number and acts indirectly to increase androgen production by the Leydig cells.
Abel, M.H. +4 more
core +1 more source
Androgen action via testicular arteriole smooth muscle cells is important for leydig cell function, vasomotion and testicular fluid dynamics [PDF]
Regulation of blood flow through the testicular microvasculature by vasomotion is thought to be important for normal testis function as it regulates interstitial fluid (IF) dynamics which is an important intra-testicular transport medium.
Bergh, A. +39 more
core +1 more source
Burned-Out Testicular Tumor: A Case Report
Germ cell tumors constitute the majority of all testicular tumors, which are relatively rare overall and are mainly encountered in young adults and teenagers.
N. Balalaa, M. Salman, W. Hassen
doaj +1 more source
Testicular fibroma: A case report and literature review
Sex cord-stromal tumors are the second most common testicular tumors after germ cell tumors. They account for about 2%–5% of adult testicular tumors. Most of these tumors are benign. The most common sex cord-stromal tumor is Leydig cell tumor.
Amal M Algarni +3 more
doaj +1 more source
Occurrence of testicular microlithiasis in androgen insensitive hypogonadal mice [PDF]
<b>Background</b>: Testicular microliths are calcifications found within the seminiferous tubules. In humans, testicular microlithiasis (TM) has an unknown etiology but may be significantly associated with testicular germ cell tumors ...
Margaret H Abel +14 more
core +1 more source
Socio-economic inequalities in testicular cancer survival within two clinical studies. [PDF]
BACKGROUND: Testicular cancer is the most common cancer in men under 35 years of age, and has the highest survival for adult male malignancies. Despite the fact that survival is very high, there is evidence that survival differs between socio-economic ...
Read, Graham +23 more
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Patients with stage I testicular germ cell tumors have a long life expectancy, but the tumors have a potential to relapse after treatment. Although relapse is observed within a few years in most cases, late relapse over 10 years after initial treatment ...
Toshirou Fukushima +6 more
doaj +1 more source
BackgroundCompared to testicular germ cell tumors, the incidence of extragonadal germ cell tumors (EGCTs) is relatively low. While the lungs are a common site for metastasis of malignant germ cell tumors, primary pulmonary germ cell tumors are extremely ...
Jian Tan +9 more
doaj +1 more source
Emerging Prognostic Biomarkers in Testicular Germ Cell Tumors: Looking Beyond Established Practice
Testicular germ cell tumors are unique among solid cancers. Historically, this disease was deadly if progressed beyond the stage I. The implementation of cisplatin-based chemotherapy regimens has drastically changed the clinical outcome of metastatic ...
Michal Chovanec +7 more
doaj +1 more source
Gastrointestinal Involvement of Testicular Germ Cell Tumor: A Case Report and Literature Review
Testicular germ cell tumors (GCT) are the commonest solid tumors in young men. Typical presentation is with painless scrotal swelling; however, symptoms related to complications or metastasis may be the initial presentation.
Oluwaseun Shogbesan +5 more
doaj +1 more source

