Results 11 to 20 of about 5,359,290 (244)

Bilateral testicular germ cell tumors [PDF]

Urology Research and Practice, 2019
Testicular cancer represents 1% to 1.5% of neoplasias in males and 5% of urologic tumors in general. The incidence of bilateral testicular tumors is 1-5%.
Haşmet Sarıcı, Onur Telli, Muzaffer Eroğlu   +2 more
doaj   +3 more sources

Epigenetics and testicular germ cell tumors [PDF]

Gene, 2018
Malignant testicular germ cell tumors (TGCTs) are the most frequent testicular cancers in Caucasian males, developing at the most productive age of man. We are briefly reviewing TGCT-tumorigenesis with an emphasis on epigenetics.
Buljubašić, Robert, Vlahović, Maja, Maja Buljubašić, Robert Buljubašić, Floriana Bulić-Jakuš, Nino Sinčić, Ana Katušić Bojanac, Bojanac, Ana Katušić, Davor Ježek, Maja Vlahović, Ulamec, Monika, Bulić-Jakuš, Floriana, Buljubašić, Maja, Ježek, Davor, Monika Ulamec, Sinčić, Nino   +15 more
core   +5 more sources

Immunotherapy in Testicular Germ Cell Tumors [PDF]

Frontiers in Oncology, 2020
Testicular germ cell tumors (TGCTs) are malignancies with very high curative potential even in metastatic settings, mainly due to the introduction of cisplatin in the treatment of this disease.
Katarina Kalavska, Katarina Kalavska, Silvia Schmidtova, Silvia Schmidtova, Michal Chovanec, Michal Mego, Michal Mego   +6 more
doaj   +3 more sources

Testicular germ cell tumors

Asian Journal of Urology, 2021
Peter Albers
doaj   +4 more sources

Biology of testicular germ cell tumors.

Expert Review of Anticancer Therapy, 2008
Germ cell tumors are derived from cells of the germ cell lineage and are the most common solid malignancies to affect young Caucasian men between the ages of 15 and 40 years.
Daniel H Palmer, Ma, Yuk; id_orcid, Syed A Hussain, Hutton, Peter, Paul Hutton, Hussain, Syed, Michael H Cullen, Palmer, Daniel, Cullen, Michael, Yuk Ting Ma   +9 more
core   +3 more sources

The Testicular Cancer Consortium (TECAC): Filling Knowledge Gaps in the Genetic Etiology of Testicular Germ Cell Tumors. [PDF]

Andrology
ABSTRACT Background The Testicular Cancer Consortium (TECAC) was established in 2012 and is comprised of researchers from over 25 centers in Europe and North America. TECAC's overarching goal is to investigate the genetic susceptibility of testicular germ cell tumors (TGCT) to better understand their biology, impact prevention strategies, and inform ...
Kanetsky PA, Almstrup K, Cherlin S, Cortessis VK, Ferlin A, Gietema JA, González-Neira A, Grotmol T, Hamilton RJ, Haugen TB, Kiemeney LA, Kim J, Krausz C, Lessel D, Lothe RA, Nead KT, Nsengimana J, Poynter JN, Rajpert-DeMeyts E, Richiardi L, Schwartz SM, Skotheim RI, Stewart DR, Turnbull C, Wiklund F, Zheng T, Nathanson KL, McGlynn KA, Testicular Cancer Consortium.   +28 more
europepmc   +2 more sources

Gonadoblastoma Arising in Undifferentiated Gonadal Tissue within Dysgenetic Gonads [PDF]

, 2006
Purpose: The purpose of the study was to define the histological origin of gonadoblastomas, allowing the identification of high-risk patients. Experimental Design: Sixty paraffin-embedded gonadectomy or gonadal biopsy samples of 43 patients with ...
Kula, Krzysztof, Stoop, Hans, Drop, Stenvert L. S, Faradz, Sultana M.H., Kersemaekers, Anne-Marie F., Cools, Martine, Looijenga, Leendert H. J, Wolffenbuttel, Katja P, Slowikowska-Hilczer, Jolanta, Bourguignon, Jean-Pierre, Oosterhuis, J. Wolter   +10 more
core   +2 more sources

Genetics of testicular germ cell tumors [PDF]

Current Opinion in Urology, 2019
Understanding the molecular basis underlying testicular germ cell tumors (TGCTs) may help improve patient outcomes, particularly for patients with poorer risk or chemoresistant disease. Here, we review the major contemporary advances in elucidating TGCT genetics by discussing patterns of TGCT inheritance, recent genomic and transcriptomic discoveries ...
Nirmish, Singla, John T, Lafin, Rashed A, Ghandour, Samuel, Kaffenberger, James F, Amatruda, Aditya, Bagrodia   +5 more
openaire   +2 more sources

Management of germ cell tumors in children: Approaches to cure [PDF]

, 2002
The introduction of cisplatinum chemotherapy and current advances in the surgical treatment have resulted in a dramatic improvement of the prognosis of children with malignant germ cell tumors (GCT).
Schneider, D. T., P. Schmidt, Schmidt, P., Haas, R. J., Göbel, U., R.J. Haas, U. Goebel, G. Calaminus, D.T. Schneider, Calaminus, G.   +9 more
core   +1 more source

Cisplatin-Based Chemotherapy for Pulmonary Metastasized Germ Cell Tumors of the Testis - Be Aware of Acute Respiratory Distress Syndrome [PDF]

, 2009
Background: Cisplatin-based combination chemotherapy is regarded as standard of care for patients with advanced germ cell tumors. In patients with lung metastases and a high tumor load, an association between induction chemotherapy and the development of
Parhofer, Klaus G., Baumann, Anja, Hausmann, Andreas, Boeck, Stefan, Metzeler, Klaus H., Gallmeier, Eike, Stemmler, Hans-Joachim   +6 more
core   +1 more source