Results 41 to 50 of about 272,521 (345)

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Numerical simulation of electrocardiograms for full cardiac cycles in healthy and pathological conditions [PDF]

, 2015
This work is dedicated to the simulation of full cycles of the electrical activity of the heart and the corresponding body surface potential. The model is based on a realistic torso and heart anatomy, including ventricles and atria.
Bayés de Luna, Bayés de Luna, Beinart, Bishop, Boulakia, Boulakia, Boulakia, Bourgault, Bueno-Orovio, Buist, Chapelle, Chapelle, Chatterjee, Cohen, Collin, Corrado, Courtemanche, Deng, Ennis, Geuzaine, Harrild, Ho, Ho, Hoekema, Hudsmith, Huiskamp, Huiskamp, Hurtadoa, Jiamsripong, Jiang, Johnson, Keller, Krishnamoorthi, Krueger, Krueger, Lines, Liu, Malmivuo, Martin, Martini, Matsuo, McGuire, Mitchell, Nash, Netter, Nielsen, Ormiston, Potse, Potse, Pullan, Rosner, Sachse, Sovilj, Streeter, Sundnes, Sundnes, Trudel, Wang, Wartak, Wei, Yan, Zwink   +61 more
core   +5 more sources

Knowledge of risk factors for gynecological cancers among medical and pharmacy students at the university of Lomé, Togo: a prospective cross-sectional study from 1 to 31 September 2021

BMC Medical Education
Introduction Gynecological cancers are often diagnosed at a late stage in Togo, due to difficulty of access to means of screening and a lack of technical platform.
Toukilnan Djiwa, Loïc Fouelifa, Mayi Bombonne, Panakinao Simgban, Tchin Darre   +4 more
doaj   +1 more source

An ontology for carcinoma classification for clinical bioinformatics [PDF]

, 2005
There are a number of existing classifications and staging schemes for carcinomas, one of the most frequently used being the TNM classification.
Kumar, Anand, Marwede, Dirk, Novotny, Daniel, Smith, Barry, Yip, Yum Lina   +4 more
core  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Nonhuman Primate Models of Respiratory Disease: Past, Present, and Future. [PDF]

, 2017
The respiratory system consists of an integrated network of organs and structures that primarily function for gas exchange. In mammals, oxygen and carbon dioxide are transmitted through a complex respiratory tract, consisting of the nasal passages ...
Miller, Lisa, Pinkerton, Kent, Royer, Christopher, Schelegle, Edward   +3 more
core   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Onchocercoma of the scalp: A case report

IDCases, 2023
Onchocerciasis or river blindness is a parasitic disease caused by Onchocerca volvulus transmitted to humans by the byte of a black fly of the species Simulium.
I. Savadogo, F.A.H.A. Ido, A.S. Ouedraogo, S. Ouattara   +3 more
doaj