Results 51 to 60 of about 1,754,279 (287)

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Behavioral addiction as a comorbidity to pathological gambling: Implication for screening and intervention in health setting

Indian Journal of Social Psychiatry, 2019
Background: Gambling has been portrayed in many anecdotes in the culture of India as an addiction associated with psychosocial dysfunctions. The present study assessed pathological gambling and other behavioral addictions as a comorbid condition in an ...
Manoj Kumar Sharma, Girish N Rao, Vivek Benegal, K Thennarasu, Divya Thomas   +4 more
doaj   +1 more source

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

Advanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho, Yein Chung, Yoonjeong Choi, Baekdong Cha, Jayeon Song, Nuri Oh, Ala Jo, Thomas S. C. Ng, Hyunho Kim, Hyun‐Kyung Woo, Chang Hyun Kim, Cesar M. Castro, Miles A. Miller, Hakho Lee   +13 more
wiley   +1 more source

Compound Abrus cantoniensis Extract Alleviates AFB1‐Induced Liver Injury by Regulating PI3K‐AKT Pathway and Gut Microbiota/Butyrate Metabolism

Advanced Science, EarlyView.
ACCE has a good alleviating effect on AFB1‐induced liver injury, and this alleviating effect is related to the PI3K‐AKT pathway regulated by ACCE and the butyrate metabolism of gut microbiota. ABSTRACT Aflatoxin B1 (AFB1) is a potent hepatotoxin commonly ingested through contaminated food. Abrus cantoniensis Hance, a traditional Chinese medicinal herb,
Hongjie Hu, Ming cheng, Shiqi Zheng, Huixin Liu, Xiaofang Wei, Wenwen Yang, Hongchun Yang, Liuyang Yuan, Li Jiang, Jie Chen, Linglong Zhao, Yanchao Guo, Hongbin Si   +12 more
wiley   +1 more source

Budaya dan Perilaku Berjudi: Kasus Tajen Di Bali

Jurnal Ilmu Perilaku, 2017
Gambling has long been comprehended as activities involving money wagering or other belongings for random or uncertain outcomes and causes the risk to chains of problems to the individuals, ranged from financial problems, psychological problems, and ...
Nyoman Trisna Aryanata
doaj   +1 more source

Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice

Advanced Science, EarlyView.
CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu, Xi‐xiu Xie, Lei Li, Chen Tian, Hao‐tian Wang, Xiao‐jie Wang, Xiao‐lin Yu, Gui‐feng Zhang, Rui‐tian Liu   +8 more
wiley   +1 more source

Prevalence and selected determinants of the risk of problem gambling among Polish secondary school students

Annals of Agricultural and Environmental Medicine, 2020
Objective The study had two aims. The first was to determine the prevalence of various types of gambling behaviour and the severity of gambling among secondary school students in one of the poorest provinces in Poland.
Iwona Niewiadomska, Lech Panasiuk, Joanna Chwaszcz, Marzena Furtak-Niczyporuk, Piotr Dreher, Karol Zygo, Janusz Jaroszyński, Aneta Mela   +7 more
doaj   +1 more source

The Victorian gambling study: a longitudinal study of gambling and health in Victoria, 2008–2012 [PDF]

, 2014
The Victorian gambling study is a longitudinal study of gambling and health in Victoria conducted between 2008 and 2012. This study is the only large-scale, general population, longitudinal gambling study conducted in Australia.
Christine Stone, Rosa Billi, Paul Marden
core  

Omnidirectional Interaction Networks Modulating Phenotypic Plasticity in the Gut Microbiota Towards Ulcerative Colitis

Advanced Science, EarlyView.
This study employs a spouse‐pair cohort design and an idopNetwork model that integrates evolutionary game theory, predator‐prey dynamics, and developmental modularity theory to reconstruct maximally informative microbial interaction networks. This approach reveals how interspecies interactions drive the phenotypic plasticity of the gut microbiota in ...
Huizhen Li, Jiayi Li, Ang Dong, Xiaoyan Guo, Qiuyue Tu, Zelin Feng, Haojia Lin, Yanru Zhang, Yuxuan Hao, Huiying Gong, Yihan Meng, Yu Wang, Shing‐Tung Yau, Xiaocang Cao, Rongling Wu, Xinjuan Liu   +15 more
wiley   +1 more source

Risk-taking and pathological gambling behavior in Huntington’s Disease

Frontiers in Behavioral Neuroscience, 2014
Huntington’s Disease (HD) is a genetic, neurodegenerative disorder, which specifically affects striatal neurons of the indirect pathway, resulting in a progressive decline in muscle coordination and loss of emotional and cognitive control. Interestingly,
Carla Elisabeth Kalkhoven, Cor eSennef, Ard ePeeters, Ruud eVan Den Bos   +3 more
doaj   +1 more source