Results 201 to 210 of about 909,959 (268)

Functional Pathological Features and Molecular Markers in Alzheimer's Disease. [PDF]

Int J Mol Sci
Park MN, Kim HW, Hong JH, Kim JK, Lee SB, Baek HS, Kwak S, Kwon YJ, Park K, Jeon J, Heo NH, Lee SH, Cho J, Kim S.   +13 more
europepmc   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Correction: Cutaneous α-Synuclein Pathology as a Differential Marker: A Histological and Statistical Comparison across Neurodegenerative Disease Groups. [PDF]

J Mol Neurosci
Šebelová D, Menšíková K, Kaiserová M, Satke L, Grambalová Z, Čížková K, Tauber Z, Klíčová K, Hraboš D, Cook SEV, Zapletalová J, Kaňovský P.   +11 more
europepmc   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Biomarkers stewardship in parkinsonism: integrating alpha-synuclein seed amplification assays and neurofilament light chain into diagnostic pathways and patient communication. [PDF]

J Neurol
Leclercq V.
europepmc   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Emerging Approaches in Breast Cancer: From Molecular Mechanisms to Diagnosis and Therapeutic Strategies. [PDF]

Oncol Res
Sanchez-Baltasar R, Castañeda-Fernández N, Olivares-Arancibia J, Torres-Villar C, Plaza-Diaz J, Herrera-Quintana L.   +5 more
europepmc   +1 more source

Gliomas with succinate dehydrogenase deficiency: A case series and brief review of the literature of oncometabolite-driven gliomagenesis. [PDF]

J Neuropathol Exp Neurol
Gray MT, Cayrol R, May A, Skaugen JM, Hayek F, Lapointe S, Hawkins CE, Pearce TM, Pratt D, Wiredja D, Toland A, Marker DF.   +11 more
europepmc   +1 more source

Cytology at the crossroads: Safeguarding equity in the molecular era. [PDF]

Cytojournal
Díaz Del Arco C.
europepmc   +1 more source

The Role of Cytology, Histology and Molecular Pathology in the Diagnostic Process of Thyroid Nodules. [PDF]

Cancers (Basel)
Ribeiro M, Canberk S, Bongiovanni M.
europepmc   +1 more source