Results 61 to 70 of about 981,501 (315)

Molecular Pathology of Poorly Differentiated and Anaplastic Thyroid Cancer: What Do Pathologists Need to Know

open access: yes, 2021
The molecular characterization of poorly and anaplastic thyroid carcinomas has been greatly improved in the last years following the advent of high throughput technologies.
Papotti, Mauro   +3 more
core   +1 more source

Clinical value of molecular pathology in glioma

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2019
Objective To summarize the clinical value of molecular pathology in glioma. Methods and Results The clinical course and molecular pathology results of 3 glioma patients were compared.
Tian⁃ming QIU   +7 more
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Application and practice of integrated diagnosis of glioma

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2019
Since the publication of the 2016 WHO of Tumors of the Central Nervous System (hereinafter referred to as 2016 WHO), many pathologists face challenges and confusion in "integrated diagnosis" practices of 2016 WHO due to financial or technical problems ...
Hai⁃nan LI, Zhi LI
doaj  

Status of Pathology Services and Molecular Pathology in Sub-Saharan Africa: Implications for Combating Breast Cancer

open access: yesKorean Journal of Clinical Laboratory Science, 2023
African breast cancer patients benefit less from classical pathology services owing to the complex molecular and clinicopathological nature of the disease, poor quality of laboratory supplies, and shortage of experts in the field.
Wajana Lako LABISSO
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Clinical Proteomics and Molecular Pathology

open access: yes, 2017
Genomic and proteomic research is launching the next era of cancer molecular medicine. Molecular expression profiles can uncover clues to functionally important molecules in the development of human disease and generate information to subclassify human ...
Weidong Zhou   +13 more
core   +1 more source

Report From the International Society of Urological Pathology (ISUP) Consultation Conference On Molecular Pathology Of Urogenital Cancers. II. Molecular Pathology of Bladder Cancer: Progress and Challenges

open access: yes, 2020
During the 2019 International Society of Urological Pathology Consultation Conference on Molecular Pathology of Urogenital Cancer, the Working Group on Bladder Cancer presented the current status and made recommendations on the diagnostic use of ...
van, der Kwast T   +19 more
core   +1 more source

GPR19 Coordinates Multiple Molecular Aspects of Stress Responses Associated with the Aging Process

open access: yes, 2023
G protein-coupled receptors (GPCRs) play a significant role in controlling biological paradigms such as aging and aging-related disease. We have previously identified receptor signaling systems that are specifically associated with controlling molecular ...
İrem Harputluoğlu   +5 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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