Results 81 to 90 of about 981,501 (315)
International Symposium of Molecular Pathology
, 2016 Office of International Symposium of Molecular Pathology (Japan-side: Kazuhisa Hasui, Kagoshima University, China-side: Xinshan Jia, China Medical ...
Office of International Symposium of Molecular Pathology (Japan-side Kazuhisa Hasui Kagoshima University China-side Xinshan Jia China Medical University) +2 more
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FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
In its first decade, The Journal of Pathology: Clinical Research has become a leading source of translational studies advancing molecular diagnostics in cancer, particularly in urologic pathology.
Acosta, Andres M., Matoso, Andres
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Understanding the Role of Dysfunctional and Healthy Mitochondria in Stroke Pathology and Its Treatment [PDF]
, 2018 Stroke remains a major cause of death and disability in the United States and around the world. Solid safety and efficacy profiles of novel stroke therapeutics have been generated in the laboratory, but most failed in clinical trials. Investigations into
Napoli, Eleonora +11 more
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The Role of Molecular Pathology in Precision Medicine: The Anatomical Pathology Perspective
Nigerian Postgraduate Medical JournalThe era of molecular pathology (MP) is gaining momentum and has tremendously changed the practice of pathology, transforming it from a morphological discipline to a molecular discipline.
Abdullahi Mohammed, Zainab Ali Adamu
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Aging and Age-Related Disorders: From Molecular Mechanisms to Therapies
, 2019 Our understanding of the molecular mechanisms underlying cellular and organismal aging and aging-associated pathology has advanced greatly in recent years [...
Vladimir I. Titorenko
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Molecular pathology in sarcomas
Clinical and Translational Oncology, 2007 Bone and soft tissue sarcomas are an infrequent group of tumours. Their prevalence is 4 in 100,000 people/year, making the disease quite rare. Some of these tumours, such as synovial sarcoma, Ewing tumour and osteosarcoma, are more usual in adolescents or in young adults; there are, though, some neoplasias such as leiomyosarcoma or liposarcoma that are
openaire +3 more sources
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Update on Molecular Genetics of Gastrointestinal Stromal Tumors
, 2021 Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. The majority are sporadic, solitary tumors that harbor mutually exclusive KIT or PDGFRA gain-of-function mutations.
Iva Brčić +2 more
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