Results 31 to 40 of about 370,051 (261)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Journal of Immunology ResearchSjögren disease (SjD) is an autoimmune disorder that predominantly affects the exocrine glands, and advancing age is recognized as an important risk factor for its development.
Mari Nishida +7 more
doaj +1 more source
Keratocystoma of palatal minor salivary glands: a case report
Journal of Oral Medicine and Oral SurgeryKeratocystoma is a rare benign tumor of the salivary glands. Initially described as a choristoma by Seifert et al. in 1999, the term “keratocystoma” was later proposed by Nagao et al. in 2001. The parotid gland is the most common site of occurrence. Only
Benaouf Souad +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Clinicopathologic Study of Oral Mucosa-Derived Hamartomas and Choristomas and Literature Review
International Journal of DentistryThis study aimed to investigate the sociodemographic and clinicopathological data of oral soft tissue hamartomas and choristomas. A cross-sectional study was delineated to quantitatively analyze oral soft tissue hamartomas and choristomas cases diagnosed
Ianca Daniele Oliveira de Jesus +6 more
doaj +1 more source
Oral Pathology in Digestive Diseases [PDF]
Modern Medicine, 2019 Correlations between alterations in the oral cavity and systemic conditions have been widely reported. A considerable number of gastrointestinal (GI) diseases of varied nature may produce lesions in the hard and soft oral tissues.
Elena POPESCU +1 more
doaj +1 more source
FEBS Letters, EarlyView.Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Histopathological Spectrum of a Calcifying Odontogenic Cyst With Uncommon Findings
Case Reports in DentistryCalcifying odontogenic cyst (COC) is an uncommon lesion accounting for less than 1% of all odontogenic cysts. This pathology commonly affects the anterior jaw and is prevalent in the second to third decades of life, with no sex predilection.
Saraswoti Khadka +6 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source