Results 101 to 110 of about 4,322,782 (345)

Pathologic diagnosis of malignant mesothelioma: chronological prospect and advent of recommendations and guidelines [PDF]

, 2015
Malignant mesothelioma is rare and difficult to diagnose. Its identification depends upon pathological investigation (cyto-histological assessment and immunohistochemistry) supported by clinical and radiological evidence.
Ascoli, Valeria
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Stem/progenitor cells in the developing human lung

Journal of Pediatric and Neonatal Individualized Medicine, 2016
Human lungs are composed of more than 40 cell types. The lung is classified as a “conditionally renewing” tissue and is able of a quick response to cellular damage thanks to the presence of multiple stem/progenitor cells.
Daniela Fanni, Margherita Fanos, Clara Gerosa, Flaviana Cau, Erika Pisu, Peter Van Eyken, Rossano Ambu   +6 more
doaj   +1 more source

Intracranial dural arteriovenous fistula successfully treated by combined open-endovascular procedure [PDF]

, 2010
Intracranial dural arteriovenous fistulas constitute a rare though potentially devastating disease. Because the arterial (high-pressure) blood flow drains directly into the low-pressure venous system, there is a high risk of bleeding and associated ...
DE KEUKELEIRE, KATRIEN, Defreyne, Luc, Hallaert, Giorgio, Van Roost, Dirk, Vanhauwaert, Dimitri J   +4 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Multiple organ failure in the newborn: the point of view of the pathologist

Journal of Pediatric and Neonatal Individualized Medicine, 2014
One of the most severe events occurring in critically ill patients admitted to a neonatal intensive care unit (NICU) center is represented by the multiple organ failure (MOF), a systemic inflammatory response leading to a progressive organ dysfunction ...
Clara Gerosa, Eleonora Obinu, Daniela Fanni, Rossano Ambu, Gavino Faa   +4 more
doaj   +1 more source

Surgical interventions for the early management of Bell's palsy [PDF]

, 2011
Background: Bell's palsy is an acute paralysis of one side of the face of unknown aetiology. Bell's palsy should only be used as a diagnosis in the absence of all other pathology.
Adour, Adour, Adour, Antoni, Aoyagi, Ballance, Brown, DerSimonian, Engstrom, Fisch, Fisch, Fisch, Friedman, Gantz, Giancarlo, Lockhart, May, May, May, McCormick, McNeill, Mechelse, Morgenlander, Peitersen, Salinas, Sillman, Spiegelhalter, Stjernquist-Desatnik, Sullivan, Theil, Yanagihara   +30 more
core   +3 more sources

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana, Mariana Maschietto, Daniela Paz Leal, Ricardo de Santos de Oliveira, Mayara Ferreira Euzébio, Antonio Carlos dos Santos, Luciano Neder, Carlos Alberto Scrideli, Elvis Terci Valera   +8 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source