Results 121 to 130 of about 4,322,782 (345)

Stem progenitor cells in the human pancreas

Journal of Pediatric and Neonatal Individualized Medicine, 2016
Early pancreas development, given its complexity, is generally considered as a paradigm for branching morphogenesis and for the development of two organs in one: the Langherans islets, programmed to secrete hormones into the bloodstream, and the exocrine
Giorgia Locci, Anna Paola Pinna, Angelica Dessì, Eleonora Obinu, Clara Gerosa, Maria Antonietta Marcialis, Maria Cristina Pintus, Marco Angiolucci, Vassilios Fanos, Rossano Ambu, Gavino Faa   +10 more
doaj   +1 more source

Method for coregistration of optical measurements of breast tissue with histopathology : the importance of accounting for tissue deformations [PDF]

, 2019
For the validation of optical diagnostic technologies, experimental results need to be benchmarked against the gold standard. Currently, the gold standard for tissue characterization is assessment of hematoxylin and eosin (H&E)-stained sections by a ...
de Boer, Lisanne L., Kho, Esther, Nijkamp, Jasper, Ruers, Theo J. M., Sterenborg, Henricus J. C. M., ter Beek, Leon C., Van de Vijver, Koen   +6 more
core   +3 more sources

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

CASE REPORT OF RHINO-CUTANEOUS MUCORMYCOSIS IN A YOUNG IMMUNOCOMPETENT PATIENT: ALERT FOR AGGRESSIVE PRESENTATIONS IN THE COMMUNITY SETTING

Brazilian Journal of Infectious Diseases
Introduction: Mucormycosis is a severe infection caused by fungi of the order Mucorales, characterized by vascular invasion and tissue necrosis. Clinical forms include rhino-cerebral, pulmonary, cutaneous, disseminated, and other rare presentations ...
Carolina Ventura Hawerroth, Ana Claudia Zezulka Machado, Douglas Augusto Pasqual La Maison, Emanuel Guerra Duarte, Daniella Serafin Couto Vieira   +4 more
doaj   +1 more source

Surgical management of extrafollicular variant of adenomatoid odontogenic tumor in the maxillary posterior region [PDF]

, 2019
Background. Adenomatoid odontogenic tumor (AOT) is a relatively uncommon benign neoplasm of odontogenic epithelial origin, accounting for less than 5% of odontogenic tumors. Case Report. The reported case describes morphological characteristics, clinical
Cristalli, Maria Paola, di Gioia, Cira Rosaria Tiziana, La Monaca, Gerardo, Pompa, Giorgio, Pranno, Nicola, Vozza, Iole   +5 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Barnes Hospital Bulletin [PDF]

, 1982
https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1202/thumbnail ...

core   +1 more source

Bilateral triad of persistent median artery, a bifid median nerve and high origin of its palmar cutaneous branch. A case report and clinical implications [PDF]

, 2016
We report the association of a persistent median artery, a bifid median nerve with a rare very high origin palmar cutaneous branch, presenting bilaterally in the upper limb of a 75-year-old female cadaver.
Ariyo, Olutayo, Shea, John
core   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source